DETERMINATION OPTIMAL CONDITIONS OF EXTRACTION OF SUM OF TRITERPENE GLYCOSIDES FROM FATSIA JAPONICA

Authors

DOI:

https://doi.org/10.52340/gs.2023.05.02.26

Keywords:

Fatsia japonica, triterpene glycosides, extraction process

Abstract

Thus, as a result of the conducted studies, the optimal mode of extraction of total triterpene glycosides from the leaves of Fatsia japonica (Thunb.) Dacne et Planch., cultivated in Georgia, has been established: extraction of triterpene glycosides from raw materials should be done with 80% ethyl alcohol for 2 hours, temperature regime 75-80° С, at the ratio of solid/liquid phases (1:5), the size of the raw material particles is 0.5-7.0 mm.

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Author Biography

Zurab Kemoklidze, Tbilisi State Medical University

Iovel Kutateladze Institute of  Pharmacochemistry

References

Ye X, Yu S, Lian XY, Zhang Z.(2014); Quantitative determination of triterpenoid glycosides in Fatsia japonica Decne. & Planch. using high performance liquid chromatography. J Pharm Biomed Anal. 88: 472-476. DOI: 10.1016/j.jpba.2013.09.017.

Wagner H. ,,Search for new Contituens with Potential Antiphlogistic and Antialergic Aqtivity” Review Planta medica vol 55 June 1989 pp 235-41.

Z. Kemoklidze, G.Dekanosidze, E.Kemertelidze. (2018). Biologically Active Triterpenoid Glycosides From Fatsia Japonica (Thunb.)Decne Et Planch) Cultivated In Georgia. Scientific-practical journal "Issues of biological,medical and pharmaceutical chemistry",10,15-18.

Tsiklauri, L., Drafi, F., Poništ, S., Slovák, L., Chrastina, M., Švík, K., Kemoklidze, Z., Kemertelidze, E., & Bauerová K. (2019). Study of anti-inflammatory activity of Fatsiphloginum (Fatsia japonica) and a new purified triterpene-rich extract of saponins (PS-551) in experimental model of arthritis. Physiological research, 68 (1), S75–S85.

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Published

2023-05-30

How to Cite

Kemoklidze, Z. (2023). DETERMINATION OPTIMAL CONDITIONS OF EXTRACTION OF SUM OF TRITERPENE GLYCOSIDES FROM FATSIA JAPONICA. Georgian Scientists, 5(2), 206–211. https://doi.org/10.52340/gs.2023.05.02.26

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