Vol. 7 No. 4 (2025)

ARTICLES

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  THE SCIENTIFIC TALKS OF MANIFESTATION OF EXOSOMES AND SMALL PARTICLE-BASED THERAPEUTICS: A COMPARATIVE REVIEW OF BIOLOGICAL AND SYNTHETIC NANOCARRIERS

  DOI : 10.52340/gs.2025.07.04.01

  Nodar Sulashvili , Valentyna Khusseyn , Dalal Hussin , Luiza Gabunia , Nana Gorgaslidze , Marika Sulashvili , Marina Giorgobiani , Irine Zarnadze , Shalva (Davit) Zarnadze , David Aphkhazava

  1-27

  Abstract : 1831

  PDF : 312

  • PDF

  DOI : 10.52340/gs.2025.07.04.01
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  THE SCIENTIFIC DISCUSSION OF KEY ISSUE ASPECTS OF EXPANDING ROLE OF PHYSICAL MEDICINE AND REHABILITATION SPECIALISTS IN MODERN MEDICINE, CLINICAL PRACTICE AND HEALTHCARE SYSTEMS IN GENERAL

  DOI : 10.52340/gs.2025.07.04.02

  Nodar Sulashvili , Valentyna Khusseyn , Dalal Hussin , Luiza Gabunia , Nana Gorgaslidze , Marika Sulashvili , Marina Giorgobiani , Irine Zarnadze , Shalva (Davit) Zarnadze , David Aphkhazava

  28-58

  Abstract : 2902

  PDF : 191

  • PDF

  DOI : 10.52340/gs.2025.07.04.02
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  PERSPECTIVES ON ENGLISH LANGUAGE ACQUISITION, ROLE AND ITS IMPACT IN ENHANCING ON EDUCATION MOBILITY, SOCIO-CULTURAL, INSTITUTIONAL INTEGRATION AND MEDICAL LABOR MARKET INTEGRATION IN EUROPE AND WORLDWIDE IN THE CONTEXT OF EDUCATIONAL GLOBALIZATION

  DOI : 10.52340/gs.2025.07.04.03

  Nodar Sulashvili , Valentyna Khusseyn , Dalal Hussin , Luiza Gabunia , Nana Gorgaslidze , Marika Sulashvili , Marina Giorgobiani , Irine Zarnadze , Shalva (Davit) Zarnadze , David Aphkhazava

  59-96

  Abstract : 1871

  PDF : 276

  • PDF

  DOI : 10.52340/gs.2025.07.04.03
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  Philosophical Origins of Cryptography Dedicated to the great Georgian scientist and my most precious teacher, Mr. Aleko Tsintsadze

  DOI : 10.52340/gs.2025.07.04.04

  Leonid-Luka Kazanji

  97-107

  Abstract : 648

  PDF : 297

  • PDF

  DOI : 10.52340/gs.2025.07.04.04
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  CHARACTERIZATION OF BIOLOGICAL TRAITS AND AGRONOMIC PERFORMANCE OF MINI KIWI (Actinidia arguta Planch.) CULTIVARS IN GEORGIA

  DOI : 10.52340/gs.2025.07.04.05

  Elene Maghlakelidze , Zviad Bobokashvili , Larisa Andronic , Tatiana Calugaru-Spataru , Svetlana Smerea

  108-125

  Abstract : 1017

  pdf : 259

  • pdf

  DOI : 10.52340/gs.2025.07.04.05
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  Molecular Heterogeneity of Melanocytic Hyperplasias, Melanocytic Moles (nevi), Markers of Recurrence and Progression

  DOI : 10.52340/gs.2025.07.04.06

  Khatuna Nodia , Tamar Saladze , George Burkadze , Shota Kepuladze

  126-145

  Abstract : 1212

  PDF : 121

  • PDF

  DOI : 10.52340/gs.2025.07.04.06
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  Analysis of Fire Development of Different Intensity in a Road Tunnel Using Numerical Simulation

  DOI : 10.52340/gs.2025.07.04.07

  Zaza Khokerashvili , Nino Ratiani , Nino Arudashvili

  146-154

  Abstract : 1343

  PDF : 96

  • PDF

  DOI : 10.52340/gs.2025.07.04.07
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  Some Considerations on Universal Research Methods in the Field of Occupational Safety

  DOI : 10.52340/gs.2025.07.04.08

  Omar Lanchava

  155-172

  Abstract : 2160

  PDF : 85

  • PDF

  DOI : 10.52340/gs.2025.07.04.08
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  Aortic Intima-media Myxoid Degeneration IMMD - A Rare Case Report

  DOI : 10.52340/gs.2025.07.04.09

  Tamar Saladze , Omar Khardzeishvili , Gigi Gorgadze , Nutsa Tsagareli , Anna Bzishvili

  173-179

  Abstract : 1340

  PDF : 439

  • PDF

  DOI : 10.52340/gs.2025.07.04.09
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  Features of Melatonin Receptor Expression in Epithelial Ovarian Tumors

  DOI : 10.52340/gs.2025.07.04.10

  Nino Imerlishvili , Zaza Bokhua , Giorgi Burkadze , Shota Kepuladze

  180-200

  Abstract : 1070

  PDF : 162

  • PDF

  DOI : 10.52340/gs.2025.07.04.10
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  Psychoanalysis of Corruption (Education System)

  DOI : 10.52340/gs.2025.07.04.11

  Giorgi Goroshidze

  201-222

  Abstract : 974

  PDF : 142

  • PDF

  DOI : 10.52340/gs.2025.07.04.11
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  On The Procedural Enhancement of Architectural Management Processes in Georgia

  DOI : 10.52340/gs.2025.07.04.12

  Pavle Sakhanberidze , Tinatin Chigogidze

  223-240

  Abstract : 1089

  PDF : 105

  • PDF

  DOI : 10.52340/gs.2025.07.04.12
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  Fractional Composition of Melanoidin Pigment

  DOI : 10.52340/gs.2025.07.04.13

  Nana Tserodze , Leila Tatiashvili , Rusudan Tsiskarishvili , Liparit Dolidze , Nona Bolkvadze , Nino Karkashadze , Rusudan Uridia

  241-247

  Abstract : 1087

  PDF : 147

  • PDF

  DOI : 10.52340/gs.2025.07.04.13
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  Why Georgia Struggles to Attract High-Spending Tourists: An Empirical Analysis of Market Readiness and Structural Barriers

  DOI : 10.52340/gs.2025.07.04.14

  Eka Gegeshidze , Zurab Garakanidze , Nino Maghradze

  248-267

  Abstract : 3050

  PDF : 128

  • PDF

  DOI : 10.52340/gs.2025.07.04.14
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  The Main Trends, Goals and Objectives of the Formation and Reform of Georgian Law on Entrepreneurs

  DOI : 10.52340/gs.2025.07.04.15

  Mariam Shavlakadze

  268-310

  Abstract : 1394

  PDF : 597

  • PDF

  DOI : 10.52340/gs.2025.07.04.15
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  The History of the Development of Herbalism: From Shamanism to Scientific Medicine

  DOI : 10.52340/gs.2025.07.04.16

  Dimitri Kochadze , Elguja Latchkepiani , Robert Makharashvili , Nana Mgaloblishvili , Dimitri Kuchukhidze , Bagdu Chkhaidze , Nikoloz Shaverdashvili , Nino Asanidze

  311-325

  Abstract : 2576

  PDF : 118

  • PDF

  DOI : 10.52340/gs.2025.07.04.16
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  Logistics Process Management Using Artificial Intelligence Optimization

  DOI : 10.52340/gs.2025.07.04.17

  Emeliane Gogilidze , Natia Gogilidze

  326-332

  Abstract : 438

  PDF : 111

  • PDF

  DOI : 10.52340/gs.2025.07.04.17
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  BIOINFORMATICS APPROACHES FOR MULTI-OMICS ANALYSIS OF THE TUMOR MICROENVIRONMENT: INTEGRATING PROTEOMICS, EXOSOMES AND IMMUNE SIGNALING

  DOI : 10.52340/gs.2025.07.04.18

  Nodar Sulashvili , Irina Imerlishvili , Seyran Kocharyan , Luiza Gabunia , Nana Gorgaslidze , Maka Buleishvili , Rajkaran Singh , Irine Zarnadze , Shalva (Davit) Zarnadze , David Aphkhazava

  333-385

  Abstract : 1952

  PDF : 233

  • PDF

  DOI : 10.52340/gs.2025.07.04.18
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  Sociological Thinking and Sociological Imagination According to Charles Wright Mills

  DOI : 10.52340/gs.2025.07.04.19

  Amiran Berdzenishvili , Kakha Ketsbaia

  386-397

  Abstract : 1580

  PDF : 150

  • PDF

  DOI : 10.52340/gs.2025.07.04.19
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  Pharmaco-botanical Study of Some Halophytic Plants of Georgia

  DOI : 10.52340/gs.2025.07.04.20

  Tsiala Ghviniashvili , Tamar Zangurashvili , Liana Jinjolia , Malkhaz Jokhadze , Dali Berashvili , Sophio Gokadze , Ana Bozhadze , Lali Zardiashvili

  398-408

  Abstract : 845

  PDF : 122

  • PDF

  DOI : 10.52340/gs.2025.07.04.20
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  Invisible Editors: Impact of AI on Media Content Quality and Trust

  DOI : 10.52340/gs.2025.07.04.21

  Mariam Arakhamia , Mariam Gersamia

  409-421

  Abstract : 946

  PDF : 332

  • PDF

  DOI : 10.52340/gs.2025.07.04.21
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  Analysis of Local and International Patents for the Microfiltration Process of Various Types of Red Wine Materials

  DOI : 10.52340/gs.2025.07.04.22

  Elene Kakabadze , George Bibileishvili , Zaza Javashvili , Leila Tananashvili , Manana Mamulashvili , Tinatin Butkhuzi , Ia Gogiberidze

  422-428

  Abstract : 1648

  PDF : 83

  • PDF

  DOI : 10.52340/gs.2025.07.04.22
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  Some Issues in Membrane Pore Size Research

  DOI : 10.52340/gs.2025.07.04.23

  George Bibileishvili , Liana Ebanoidze , Nana Gogesashvili , Liana Kuparadze , Tinatin Butkhuzi , Ia Gogiberidze

  429-434

  Abstract : 2116

  PDF : 353

  • PDF

  DOI : 10.52340/gs.2025.07.04.23
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  Colloidal-chemical Study of Sediment Formed Natural Water on a Microfiltration Membrane

  DOI : 10.52340/gs.2025.07.04.24

  George Bibileishvili , Liana Ebanoidze , Mzia Kezherashvili , Manana Mamulashvili , Liana Kuparadze , Nona Butkhuzi , Ia Gogiberidze

  435-439

  Abstract : 907

  PDF : 89

  • PDF

  DOI : 10.52340/gs.2025.07.04.24
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  Microbiological Analysis of Wastewater, Fruit Juices, Determination of Microbial Sizes, Diagnostics and Filtration of Microorganisms

  DOI : 10.52340/gs.2025.07.04.25

  George Bibileishvili , Manana Mamulashvili , Elene Kakabadze , Liana Ebanoidze , Nona Butkhuzi , Ia Gogiberidze

  440-443

  Abstract : 864

  PDF : 95

  • PDF

  DOI : 10.52340/gs.2025.07.04.25
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  Investigation of Optimal Mode Parameters of Nanofiltration Separation Process

  DOI : 10.52340/gs.2025.07.04.26

  George Bibileishvili , Mzia Kezherashvili , Zaza Javashvili , Nana Gogesashvili , Elene Kakabadze , Nona Butkhuzi

  444-448

  Abstract : 931

  PDF : 104

  • PDF

  DOI : 10.52340/gs.2025.07.04.26
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  Methods for Staining Microbial Capsules and Spores in the Microbiological Study of Rkatsiteli Wine Materials and Fruit Juices

  DOI : 10.52340/gs.2025.07.04.27

  George Bibileishvili , Tinatin Butkhuzi , Manana Mamulashvili , Liana Ebanoidze , Leila Tananashvili , Ia Gogiberidze

  449-452

  Abstract : 1284

  PDF : 129

  • PDF

  DOI : 10.52340/gs.2025.07.04.27
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  Effect of Phase Inversion Temperature on the Formation and Performance of PES/DMF/PVP Polyethersulfone Membranes

  DOI : 10.52340/gs.2025.07.04.28

  Nana Gogesashvili , Giorgi Bibileishvili , Zaza Javashvili , Mzia Kezherashvili , Liana Kuparadze , Nona Butkhuzi

  453-460

  Abstract : 840

  PDF : 125

  • PDF

  DOI : 10.52340/gs.2025.07.04.28
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  Preparation and Study of Membranes for the Microfiltration Process of Sterilization of Black Grape Wine Material

  DOI : 10.52340/gs.2025.07.04.29

  George Bibileishvili , Nana Gogesashvili , Manana Mamulashvili , Liana Ebanoidze , Elene Kakabadze , Tinatin Butkhuzi

  461-467

  Abstract : 876

  PDF : 111

  • PDF

  DOI : 10.52340/gs.2025.07.04.29
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  Theoretical and Experimental Studies of the Nanofiltration Separation Process under Laminar Flow Conditions

  DOI : 10.52340/gs.2025.07.04.30

  Liana Kuparadze , Giorgi Bibileishvili , Nana Gogesashvili , Tinatin Butkhuzi , Nona Butkhuzi , Ia Gogiberidze

  468-473

  Abstract : 713

  PDF : 84

  • PDF

  DOI : 10.52340/gs.2025.07.04.30
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  Challenges and Opportunities for Ensuring Environmental Protection Requirements

  DOI : 10.52340/gs.2025.07.04.31

  Merab Baratashvili , Tornike Baratashvili

  474-484

  Abstract : 1241

  PDF : 98

  • PDF

  DOI : 10.52340/gs.2025.07.04.31
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  Possibilities of Using Fiber-optic Sensors in Train Movement Control Systems

  DOI : 10.52340/gs.2025.07.04.32

  Merab Gotsadze , Avtandil Sharvashidze , Tengiz Tabidze

  485-492

  Abstract : 610

  PDF : 94

  • PDF

  DOI : 10.52340/gs.2025.07.04.32
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  DEVELOPMENT OF SUPPOSITORIES CONTAINING SEA BUCKTHORN OIL AND THYMOL

  DOI : 10.52340/gs.2025.07.04.33

  Dimitri Lagazidze , Tamuna Benashvili , Manana Orjonikidze , Bela Kikalishvili , Malkhaz Getia , Alyosha Bakuridze

  493-501

  Abstract : 853

  PDF : 128

  • PDF

  DOI : 10.52340/gs.2025.07.04.33
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  A Narrative Review of the Diagnostic Performance of Non-Invasive Scores for Predicting Fibrosis in MAFLD

  DOI : 10.52340/gs.2025.07.04.34

  Tatia Khachidze , Gela Sulaberidze , Gocha Barbakadze

  502-514

  Abstract : 527

  PDF : 132

  • PDF

  DOI : 10.52340/gs.2025.07.04.34
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  Evaluation of Clinical, Laboratory, and Imaging Progression and Prognostic Outcomes in Patients with Post-COVID-19 Pneumonia Literature Review

  DOI : 10.52340/gs.2025.07.04.35

  Marina Kuparadze , Giorgi Imedashvili , Nino Gegeshidze , Xatuna Chaava , Mariam Morchiladze , Tamila Silagadze

  515-522

  Abstract : 546

  PDF : 111

  • PDF

  DOI : 10.52340/gs.2025.07.04.35
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  Localization of Water-related Toponyms and Hydronyms in the Speech of the Prone Valley

  DOI : 10.52340/gs.2025.07.04.36

  Mariam Koberidze

  523-531

  Abstract : 799

  PDF : 113

  • PDF

  DOI : 10.52340/gs.2025.07.04.36
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  Key Challenges in AI-Powered Translation in the Context of the Georgian Language

  DOI : 10.52340/gs.2025.07.04.37

  Maia Nachkepia

  532-542

  Abstract : 1464

  PDF : 167

  • PDF

  DOI : 10.52340/gs.2025.07.04.37
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  The Critical Role of Investment Banks in the Sustainable Growth of Emerging Economies: the Case of Georgia

  DOI : 10.52340/gs.2025.07.04.38

  Giorgi Turazashvili

  543-556

  Abstract : 1574

  PDF : 111

  • PDF

  DOI : 10.52340/gs.2025.07.04.38
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  Peculiarities of Changes in the Proliferative Activity and Inflammatory Index of the Osteochondral Component and Synovial Membrane of the Hip Joint during Coxarthrosis

  DOI : 10.52340/gs.2025.07.04.39

  Nino Kavtaradze , Elene-Dodo Kartvelishvili , Magda Jangiani , George Burkadze

  557-570

  Abstract : 1158

  PDF : 103

  • PDF

  DOI : 10.52340/gs.2025.07.04.39
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  Acquisition of Hard-to-detect Objects in Airspace, Utilizing Modulated Laser Radiation for Perimeter Control

  DOI : 10.52340/gs.2025.07.04.40

  Shalva Kakabadze , Tengiz Khachidze , Guram Chaganava , Inga Kapanadze , Nikoloz Khachidze

  571-577

  Abstract : 437

  PDF : 107

  • PDF

  DOI : 10.52340/gs.2025.07.04.40
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  Fifth Generation (5G) Networks’s Implementation State in Countries around the World

  DOI : 10.52340/gs.2025.07.04.41

  Salome Makharadze , Taliko Mikava , Gigi Khunashvili

  578-592

  Abstract : 787

  pdf : 390

  • pdf

  DOI : 10.52340/gs.2025.07.04.41
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  THE MANIFESTATION OF FEATURES OF GENE THERAPY ADVANCES: A COMPREHENSIVE DISCOURSE OF CURRENT PROGRESS AND FUTURE DIRECTIONS

  DOI : 10.52340/gs.2025.07.04.42

  Nodar Sulashvili , Naira Chichoyan , Vira Kravchenko , Irina Imerlishvili , Luiza Gabunia , Nana Gorgaslidze , Maka Buleishvili , Marika Sulashvili , Rajkaran Singh , Deva Harsha Uday Gundluru , David Aphkhazava

  593-620

  Abstract : 2145

  PDF : 170

  • PDF

  DOI : 10.52340/gs.2025.07.04.42
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  Hepatitis B in Georgia: Progress, Gaps, and Equity Across the Prevention-to-Care Cascade

  DOI : 10.52340/gs.2025.07.04.43

  Lela Inaishvili , Tamriko Bulia , Lali Sharvadze , Nikoloz Pruidze

  621-629

  Abstract : 1449

  PDF : 170

  • PDF

  DOI : 10.52340/gs.2025.07.04.43
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  ADVANCES, CLINICAL TRANSLATION AND EMERGING CHALLENGES IN GENE THERAPY: FROM VIRAL VECTOR ENGINEERING AND GENOME EDITING TO PRECISION AND PERSONALIZED GENETIC MEDICINE

  DOI : 10.52340/gs.2025.07.04.44

  Nodar Sulashvili , Igor Seniuk , Vira Kravchenko , Irina Imerlishvili , Luiza Gabunia , Nana Gorgaslidze , Maka Buleishvili , Marika Sulashvili , Rajkaran Singh , Deva Harsha Uday Gundluru , David Aphkhazava

  630-656

  Abstract : 2078

  PDF : 184

  • PDF

  DOI : 10.52340/gs.2025.07.04.44
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  Application of Polyphenol (Tannin)-Rich Leaf Extracts of Cotinus coggygria Scop., Cultivated in Georgia, in Endodontic Practice

  DOI : 10.52340/gs.2025.07.04.45

  Tamar Shavadze , Natia Nizharadze , Marina Mamaladze , Ketevan Shalashvili , Malkhaz Getia , Karen Mulkijaniani , Eter Kemertelidze

  657-667

  Abstract : 1621

  PDF : 132

  • PDF

  DOI : 10.52340/gs.2025.07.04.45
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  Risk Analysis and Control of Information Systems in ISO/IEC 17025 Accredited Testing Laboratories

  DOI : 10.52340/gs.2025.07.04.46

  Nino Lortkipanidze

  668-679

  Abstract : 1369

  PDF : 167

  • PDF

  DOI : 10.52340/gs.2025.07.04.46
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  Identification and Documentation of Endemic Grapevine Varieties in Samegrelo

  DOI : 10.52340/gs.2025.07.04.47

  Londa Mamasakhlisashvili , Maia Mirvelashvili , Olan Gotsiridze , Naira Kenchiashvili , Lia Megrelishvili

  680-692

  Abstract : 1161

  PDF : 90

  • PDF

  DOI : 10.52340/gs.2025.07.04.47
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  Palliative Care in the 21st Century: Multidisciplinary Collaboration, Digital Health, and Equitable Access

  DOI : 10.52340/gs.2025.07.04.48

  Tamriko Bulia , Tina Beruchashvili , Ioseb Abesadze , Ekaterine Abzianidze , Bakho Dvali , Lela Inaishvili

  693-704

  Abstract : 2525

  PDF : 95

  • PDF

  DOI : 10.52340/gs.2025.07.04.48
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  A Lightweight and Optimized BERT-based Intrusion Detection System for Resource-Constrained Network and Logistics Environments

  DOI : 10.52340/gs.2025.07.04.49

  Vartan Mamikonian , Djemal Mamamniashvili

  705-714

  Abstract : 2384

  PDF : 119

  • PDF

  DOI : 10.52340/gs.2025.07.04.49