Design and Technological Optimization of Cosmetic Sticks Enriched with Antibacterial Sage Extract

Modern pharmacies are rich in a variety of cosmetic products, but most of them are based on components of synthetic origin. Their use often causes various complications and allergic reactions, which is why both patients and doctors prefer cosmetics made from natural ingredients.

       Among skin care cosmetic products, cosmetic sticks hold a special place. Medical cosmetic sticks are characterised by their ability to act on specific/local areas of the skin and mucous membranes for an extended period. They are portable, convenient to use, and thanks to their special packaging, they are hygienic, economical, and have an extended shelf life. One of the key advantages of medicinal cosmetic sticks is the ability to incorporate naturally derived components (such as plant extracts, essential oils, clays, muds, etc.) due to the natural origin of their base. The assortment of medicinal cosmetic sticks in pharmacies is currently limited. Therefore, the study and development of formulations for medicinal cosmetic sticks, and their production using modern technologies for various purposes, is a pressing issue in contemporary pharmacy.

     That is why  we aimed to develop the formulation, design and biological evaluation of antibacterial treatment cosmetic sticks developed on natural products.

      Active pharmaceutical ingredients of the sticks  (mixture of sage dry extract and essential oil) proved to have high antibacterial activity against Streptococcus pyogenes, Escherichia coli, Salmo­nella typhimurium, Klebsiella pneumoniae, Proteus vulgaris, Shigella flexneri, Enterococcus faecalis   and Staphylococcus aureus (in vitro - “Spot Test”).

       Based on a result literature review and the study of organoleptic, physico-chemical and technological characteristics, nine optimal sticks formulations were selected. We have studied the qualitative indicators of research composition nine and among them, sticks research composition No. 9 is characterized by the best characteristics with the following composition (for 10 sticks, weight of each sticks is 2.4): paraffin 2.0g; castor oil 10.0g; cocoa fat 2.0g; emulsion wax 3.94g; beeswax 2.0g; lanolin 2.0g; dry extract of sage grass 2.0g; Sage essential oil 0.06g. On the basis of technological studies, the technological scheme and technological process of sticks with antibacterial action have been developed, the material balances of the technological process of making sticks have been drawn up and the technical-economic indicators have been determined.