4. Health Sciences 4.1 Medicine 

Aortic Intima-media Myxoid Degeneration IMMD - A Rare Case Report

Cardiology Cardio surgery Vessels Aneurysms oid/Myxoid degeneration of aorta: Acute decompensated heart failure

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November 3, 2025

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Introduction: Aortic intima-media myxoid (IMMD) degeneration, often leading to valve insufficient by myxomatous tissue, is also known as aortic mucoid degeneration which also Leeds “cystic medial degeneration” involving the accumulation of mucin within the medial layer of the aorta, both are rare vascular disease characterized by the degenerative process in different layers of the arterial wall, which leads to formation of aneurysms at the damaged side. Patients with myxoid degeneration often have aneurysms at any location in the artery and postoperative bleedings are also common.

Case report: We describe three cases of material obtained by the cardio surgical method. Histopathological diagnosis: idiopathic aortic intima-media myxoid degeneration. Clinical cases reports are also provided, since such a pathology has not been described in the literature available to us.

Discussion: Acute decompensated heart failure may be caused by intima-media myxoid degeneration of the aorta. Aneurysms are common. Surgical treatment may be complicated by intra and postoperative bleeding, which requires caution during surgical intervention and specific postoperative management.

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