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Vol. 7 No. 4 (2025)

View Vol. 7 No. 4 (2025)

Published: 2025-10-04

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ARTICLES

THE SCIENTIFIC TALKS OF MANIFESTATION OF EXOSOMES AND SMALL PARTICLE-BASED THERAPEUTICS: A COMPARATIVE REVIEW OF BIOLOGICAL AND SYNTHETIC NANOCARRIERS

DOI : 10.52340/gs.2025.07.04.01

Nodar Sulashvili , Valentyna Khusseyn , Dalal Hussin , Luiza Gabunia , Nana Gorgaslidze , Marika Sulashvili , Marina Giorgobiani , Irine Zarnadze , Shalva (Davit) Zarnadze , David Aphkhazava

1-27

Abstract : 765

PDF : 92
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DOI : 10.52340/gs.2025.07.04.01
THE SCIENTIFIC DISCUSSION OF KEY ISSUE ASPECTS OF EXPANDING ROLE OF PHYSICAL MEDICINE AND REHABILITATION SPECIALISTS IN MODERN MEDICINE, CLINICAL PRACTICE AND HEALTHCARE SYSTEMS IN GENERAL

DOI : 10.52340/gs.2025.07.04.02

Nodar Sulashvili , Valentyna Khusseyn , Dalal Hussin , Luiza Gabunia , Nana Gorgaslidze , Marika Sulashvili , Marina Giorgobiani , Irine Zarnadze , Shalva (Davit) Zarnadze , David Aphkhazava

28-58

Abstract : 1295

PDF : 67
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DOI : 10.52340/gs.2025.07.04.02
PERSPECTIVES ON ENGLISH LANGUAGE ACQUISITION, ROLE AND ITS IMPACT IN ENHANCING ON EDUCATION MOBILITY, SOCIO-CULTURAL, INSTITUTIONAL INTEGRATION AND MEDICAL LABOR MARKET INTEGRATION IN EUROPE AND WORLDWIDE IN THE CONTEXT OF EDUCATIONAL GLOBALIZATION

DOI : 10.52340/gs.2025.07.04.03

Nodar Sulashvili , Valentyna Khusseyn , Dalal Hussin , Luiza Gabunia , Nana Gorgaslidze , Marika Sulashvili , Marina Giorgobiani , Irine Zarnadze , Shalva (Davit) Zarnadze , David Aphkhazava

59-96

Abstract : 825

PDF : 94
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DOI : 10.52340/gs.2025.07.04.03
Philosophical Origins of Cryptography Dedicated to the great Georgian scientist and my most precious teacher, Mr. Aleko Tsintsadze

DOI : 10.52340/gs.2025.07.04.04

Leonid-Luka Kazanji

97-107

Abstract : 262

PDF : 98
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DOI : 10.52340/gs.2025.07.04.04
CHARACTERIZATION OF BIOLOGICAL TRAITS AND AGRONOMIC PERFORMANCE OF MINI KIWI (Actinidia arguta Planch.) CULTIVARS IN GEORGIA

DOI : 10.52340/gs.2025.07.04.05

Elene Maghlakelidze , Zviad Bobokashvili , Larisa Andronic , Tatiana Calugaru-Spataru , Svetlana Smerea

108-125

Abstract : 451

pdf : 88
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DOI : 10.52340/gs.2025.07.04.05
Molecular Heterogeneity of Melanocytic Hyperplasias, Melanocytic Moles (nevi), Markers of Recurrence and Progression

DOI : 10.52340/gs.2025.07.04.06

Khatuna Nodia , Tamar Saladze , George Burkadze , Shota Kepuladze

126-145

Abstract : 478

PDF : 30
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DOI : 10.52340/gs.2025.07.04.06
Analysis of Fire Development of Different Intensity in a Road Tunnel Using Numerical Simulation

DOI : 10.52340/gs.2025.07.04.07

Zaza Khokerashvili , Nino Ratiani , Nino Arudashvili

146-154

Abstract : 560

PDF : 34
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DOI : 10.52340/gs.2025.07.04.07
Some Considerations on Universal Research Methods in the Field of Occupational Safety

DOI : 10.52340/gs.2025.07.04.08

Omar Lanchava

155-172

Abstract : 873

PDF : 31
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DOI : 10.52340/gs.2025.07.04.08
Aortic Intima-media Myxoid Degeneration IMMD - A Rare Case Report

DOI : 10.52340/gs.2025.07.04.09

Tamar Saladze , Omar Khardzeishvili , Gigi Gorgadze , Nutsa Tsagareli , Anna Bzishvili

173-179

Abstract : 661

PDF : 153
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DOI : 10.52340/gs.2025.07.04.09
Features of Melatonin Receptor Expression in Epithelial Ovarian Tumors

DOI : 10.52340/gs.2025.07.04.10

Nino Imerlishvili , Zaza Bokhua , Giorgi Burkadze , Shota Kepuladze

180-200

Abstract : 593

PDF : 55
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DOI : 10.52340/gs.2025.07.04.10
Psychoanalysis of Corruption (Education System)

DOI : 10.52340/gs.2025.07.04.11

Giorgi Goroshidze

201-222

Abstract : 432

PDF : 61
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DOI : 10.52340/gs.2025.07.04.11
On The Procedural Enhancement of Architectural Management Processes in Georgia

DOI : 10.52340/gs.2025.07.04.12

Pavle Sakhanberidze , Tinatin Chigogidze

223-240

Abstract : 520

PDF : 33
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DOI : 10.52340/gs.2025.07.04.12
Fractional Composition of Melanoidin Pigment

DOI : 10.52340/gs.2025.07.04.13

Nana Tserodze , Leila Tatiashvili , Rusudan Tsiskarishvili , Liparit Dolidze , Nona Bolkvadze , Nino Karkashadze , Rusudan Uridia

241-247

Abstract : 488

PDF : 54
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DOI : 10.52340/gs.2025.07.04.13
Why Georgia Struggles to Attract High-Spending Tourists: An Empirical Analysis of Market Readiness and Structural Barriers

DOI : 10.52340/gs.2025.07.04.14

Eka Gegeshidze , Zurab Garakanidze , Nino Maghradze

248-267

Abstract : 1461

PDF : 44
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DOI : 10.52340/gs.2025.07.04.14
The Main Trends, Goals and Objectives of the Formation and Reform of Georgian Law on Entrepreneurs

DOI : 10.52340/gs.2025.07.04.15

Mariam Shavlakadze

268-310

Abstract : 605

PDF : 342
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DOI : 10.52340/gs.2025.07.04.15
The History of the Development of Herbalism: From Shamanism to Scientific Medicine

DOI : 10.52340/gs.2025.07.04.16

Dimitri Kochadze , Elguja Latchkepiani , Robert Makharashvili , Nana Mgaloblishvili , Dimitri Kuchukhidze , Bagdu Chkhaidze , Nikoloz Shaverdashvili , Nino Asanidze

311-325

Abstract : 1048

PDF : 48
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DOI : 10.52340/gs.2025.07.04.16
Logistics Process Management Using Artificial Intelligence Optimization

DOI : 10.52340/gs.2025.07.04.17

Emeliane Gogilidze , Natia Gogilidze

326-332

Abstract : 175

PDF : 36
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DOI : 10.52340/gs.2025.07.04.17
BIOINFORMATICS APPROACHES FOR MULTI-OMICS ANALYSIS OF THE TUMOR MICROENVIRONMENT: INTEGRATING PROTEOMICS, EXOSOMES AND IMMUNE SIGNALING

DOI : 10.52340/gs.2025.07.04.18

Nodar Sulashvili , Irina Imerlishvili , Seyran Kocharyan , Luiza Gabunia , Nana Gorgaslidze , Maka Buleishvili , Rajkaran Singh , Irine Zarnadze , Shalva (Davit) Zarnadze , David Aphkhazava

333-385

Abstract : 828

PDF : 105
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DOI : 10.52340/gs.2025.07.04.18
Sociological Thinking and Sociological Imagination According to Charles Wright Mills

DOI : 10.52340/gs.2025.07.04.19

Amiran Berdzenishvili , Kakha Ketsbaia

386-397

Abstract : 654

PDF : 49
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DOI : 10.52340/gs.2025.07.04.19
Pharmaco-botanical Study of Some Halophytic Plants of Georgia

DOI : 10.52340/gs.2025.07.04.20

Tsiala Ghviniashvili , Tamar Zangurashvili , Liana Jinjolia , Malkhaz Jokhadze , Dali Berashvili , Sophio Gokadze , Ana Bozhadze , Lali Zardiashvili

398-408

Abstract : 426

PDF : 48
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DOI : 10.52340/gs.2025.07.04.20
Invisible Editors: Impact of AI on Media Content Quality and Trust

DOI : 10.52340/gs.2025.07.04.21

Mariam Arakhamia , Mariam Gersamia

409-421

Abstract : 448

PDF : 131
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DOI : 10.52340/gs.2025.07.04.21
Analysis of Local and International Patents for the Microfiltration Process of Various Types of Red Wine Materials

DOI : 10.52340/gs.2025.07.04.22

Elene Kakabadze , George Bibileishvili , Zaza Javashvili , Leila Tananashvili , Manana Mamulashvili , Tinatin Butkhuzi , Ia Gogiberidze

422-428

Abstract : 748

PDF : 35
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DOI : 10.52340/gs.2025.07.04.22
Some Issues in Membrane Pore Size Research

DOI : 10.52340/gs.2025.07.04.23

George Bibileishvili , Liana Ebanoidze , Nana Gogesashvili , Liana Kuparadze , Tinatin Butkhuzi , Ia Gogiberidze

429-434

Abstract : 880

PDF : 121
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DOI : 10.52340/gs.2025.07.04.23
Colloidal-chemical Study of Sediment Formed Natural Water on a Microfiltration Membrane

DOI : 10.52340/gs.2025.07.04.24

George Bibileishvili , Liana Ebanoidze , Mzia Kezherashvili , Manana Mamulashvili , Liana Kuparadze , Nona Butkhuzi , Ia Gogiberidze

435-439

Abstract : 393

PDF : 40
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DOI : 10.52340/gs.2025.07.04.24
Microbiological Analysis of Wastewater, Fruit Juices, Determination of Microbial Sizes, Diagnostics and Filtration of Microorganisms

DOI : 10.52340/gs.2025.07.04.25

George Bibileishvili , Manana Mamulashvili , Elene Kakabadze , Liana Ebanoidze , Nona Butkhuzi , Ia Gogiberidze

440-443

Abstract : 360

PDF : 40
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DOI : 10.52340/gs.2025.07.04.25
Investigation of Optimal Mode Parameters of Nanofiltration Separation Process

DOI : 10.52340/gs.2025.07.04.26

George Bibileishvili , Mzia Kezherashvili , Zaza Javashvili , Nana Gogesashvili , Elene Kakabadze , Nona Butkhuzi

444-448

Abstract : 548

PDF : 38
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DOI : 10.52340/gs.2025.07.04.26
Methods for Staining Microbial Capsules and Spores in the Microbiological Study of Rkatsiteli Wine Materials and Fruit Juices

DOI : 10.52340/gs.2025.07.04.27

George Bibileishvili , Tinatin Butkhuzi , Manana Mamulashvili , Liana Ebanoidze , Leila Tananashvili , Ia Gogiberidze

449-452

Abstract : 584

PDF : 40
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DOI : 10.52340/gs.2025.07.04.27
Effect of Phase Inversion Temperature on the Formation and Performance of PES/DMF/PVP Polyethersulfone Membranes

DOI : 10.52340/gs.2025.07.04.28

Nana Gogesashvili , Giorgi Bibileishvili , Zaza Javashvili , Mzia Kezherashvili , Liana Kuparadze , Nona Butkhuzi

453-460

Abstract : 413

PDF : 42
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DOI : 10.52340/gs.2025.07.04.28
Preparation and Study of Membranes for the Microfiltration Process of Sterilization of Black Grape Wine Material

DOI : 10.52340/gs.2025.07.04.29

George Bibileishvili , Nana Gogesashvili , Manana Mamulashvili , Liana Ebanoidze , Elene Kakabadze , Tinatin Butkhuzi

461-467

Abstract : 368

PDF : 43
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DOI : 10.52340/gs.2025.07.04.29
Theoretical and Experimental Studies of the Nanofiltration Separation Process under Laminar Flow Conditions

DOI : 10.52340/gs.2025.07.04.30

Liana Kuparadze , Giorgi Bibileishvili , Nana Gogesashvili , Tinatin Butkhuzi , Nona Butkhuzi , Ia Gogiberidze

468-473

Abstract : 313

PDF : 23
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DOI : 10.52340/gs.2025.07.04.30
Challenges and Opportunities for Ensuring Environmental Protection Requirements

DOI : 10.52340/gs.2025.07.04.31

Merab Baratashvili , Tornike Baratashvili

474-484

Abstract : 483

PDF : 31
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DOI : 10.52340/gs.2025.07.04.31
Possibilities of Using Fiber-optic Sensors in Train Movement Control Systems

DOI : 10.52340/gs.2025.07.04.32

Merab Gotsadze , Avtandil Sharvashidze , Tengiz Tabidze

485-492

Abstract : 353

PDF : 33
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DOI : 10.52340/gs.2025.07.04.32
DEVELOPMENT OF SUPPOSITORIES CONTAINING SEA BUCKTHORN OIL AND THYMOL

DOI : 10.52340/gs.2025.07.04.33

Dimitri Lagazidze , Tamuna Benashvili , Manana Orjonikidze , Bela Kikalishvili , Malkhaz Getia , Alyosha Bakuridze

493-501

Abstract : 381

PDF : 48
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DOI : 10.52340/gs.2025.07.04.33
A Narrative Review of the Diagnostic Performance of Non-Invasive Scores for Predicting Fibrosis in MAFLD

DOI : 10.52340/gs.2025.07.04.34

Tatia Khachidze , Gela Sulaberidze , Gocha Barbakadze

502-514

Abstract : 204

PDF : 42
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DOI : 10.52340/gs.2025.07.04.34
Evaluation of Clinical, Laboratory, and Imaging Progression and Prognostic Outcomes in Patients with Post-COVID-19 Pneumonia Literature Review

DOI : 10.52340/gs.2025.07.04.35

Marina Kuparadze , Giorgi Imedashvili , Nino Gegeshidze , Xatuna Chaava , Mariam Morchiladze , Tamila Silagadze

515-522

Abstract : 194

PDF : 31
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DOI : 10.52340/gs.2025.07.04.35
Localization of Water-related Toponyms and Hydronyms in the Speech of the Prone Valley

DOI : 10.52340/gs.2025.07.04.36

Mariam Koberidze

523-531

Abstract : 360

PDF : 55
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DOI : 10.52340/gs.2025.07.04.36
Key Challenges in AI-Powered Translation in the Context of the Georgian Language

DOI : 10.52340/gs.2025.07.04.37

Maia Nachkepia

532-542

Abstract : 607

PDF : 57
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DOI : 10.52340/gs.2025.07.04.37
The Critical Role of Investment Banks in the Sustainable Growth of Emerging Economies: the Case of Georgia

DOI : 10.52340/gs.2025.07.04.38

Giorgi Turazashvili

543-556

Abstract : 704

PDF : 37
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DOI : 10.52340/gs.2025.07.04.38
Peculiarities of Changes in the Proliferative Activity and Inflammatory Index of the Osteochondral Component and Synovial Membrane of the Hip Joint during Coxarthrosis

DOI : 10.52340/gs.2025.07.04.39

Nino Kavtaradze , Elene-Dodo Kartvelishvili , Magda Jangiani , George Burkadze

557-570

Abstract : 427

PDF : 31
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DOI : 10.52340/gs.2025.07.04.39
Acquisition of Hard-to-detect Objects in Airspace, Utilizing Modulated Laser Radiation for Perimeter Control

DOI : 10.52340/gs.2025.07.04.40

Shalva Kakabadze , Tengiz Khachidze , Guram Chaganava , Inga Kapanadze , Nikoloz Khachidze

571-577

Abstract : 180

PDF : 42
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DOI : 10.52340/gs.2025.07.04.40
Fifth Generation (5G) Networks’s Implementation State in Countries around the World

DOI : 10.52340/gs.2025.07.04.41

Salome Makharadze , Taliko Mikava , Gigi Khunashvili

578-592

Abstract : 344

pdf : 122
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DOI : 10.52340/gs.2025.07.04.41
THE MANIFESTATION OF FEATURES OF GENE THERAPY ADVANCES: A COMPREHENSIVE DISCOURSE OF CURRENT PROGRESS AND FUTURE DIRECTIONS

DOI : 10.52340/gs.2025.07.04.42

Nodar Sulashvili , Naira Chichoyan , Vira Kravchenko , Irina Imerlishvili , Luiza Gabunia , Nana Gorgaslidze , Maka Buleishvili , Marika Sulashvili , Rajkaran Singh , Deva Harsha Uday Gundluru , David Aphkhazava

593-620

Abstract : 826

PDF : 70
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DOI : 10.52340/gs.2025.07.04.42
Hepatitis B in Georgia: Progress, Gaps, and Equity Across the Prevention-to-Care Cascade

DOI : 10.52340/gs.2025.07.04.43

Lela Inaishvili , Tamriko Bulia , Lali Sharvadze , Nikoloz Pruidze

621-629

Abstract : 577

PDF : 73
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DOI : 10.52340/gs.2025.07.04.43
ADVANCES, CLINICAL TRANSLATION AND EMERGING CHALLENGES IN GENE THERAPY: FROM VIRAL VECTOR ENGINEERING AND GENOME EDITING TO PRECISION AND PERSONALIZED GENETIC MEDICINE

DOI : 10.52340/gs.2025.07.04.44

Nodar Sulashvili , Igor Seniuk , Vira Kravchenko , Irina Imerlishvili , Luiza Gabunia , Nana Gorgaslidze , Maka Buleishvili , Marika Sulashvili , Rajkaran Singh , Deva Harsha Uday Gundluru , David Aphkhazava

630-656

Abstract : 748

PDF : 74
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DOI : 10.52340/gs.2025.07.04.44
Application of Polyphenol (Tannin)-Rich Leaf Extracts of Cotinus coggygria Scop., Cultivated in Georgia, in Endodontic Practice

DOI : 10.52340/gs.2025.07.04.45

Tamar Shavadze , Natia Nizharadze , Marina Mamaladze , Ketevan Shalashvili , Malkhaz Getia , Karen Mulkijaniani , Eter Kemertelidze

657-667

Abstract : 676

PDF : 46
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DOI : 10.52340/gs.2025.07.04.45
Risk Analysis and Control of Information Systems in ISO/IEC 17025 Accredited Testing Laboratories

DOI : 10.52340/gs.2025.07.04.46

Nino Lortkipanidze

668-679

Abstract : 591

PDF : 63
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DOI : 10.52340/gs.2025.07.04.46
Identification and Documentation of Endemic Grapevine Varieties in Samegrelo

DOI : 10.52340/gs.2025.07.04.47

Londa Mamasakhlisashvili , Maia Mirvelashvili , Olan Gotsiridze , Naira Kenchiashvili , Lia Megrelishvili

680-692

Abstract : 434

PDF : 27
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DOI : 10.52340/gs.2025.07.04.47
Palliative Care in the 21st Century: Multidisciplinary Collaboration, Digital Health, and Equitable Access

DOI : 10.52340/gs.2025.07.04.48

Tamriko Bulia , Tina Beruchashvili , Ioseb Abesadze , Ekaterine Abzianidze , Bakho Dvali , Lela Inaishvili

693-704

Abstract : 1023

PDF : 29
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DOI : 10.52340/gs.2025.07.04.48
A Lightweight and Optimized BERT-based Intrusion Detection System for Resource-Constrained Network and Logistics Environments

DOI : 10.52340/gs.2025.07.04.49

Vartan Mamikonian , Djemal Mamamniashvili

705-714

Abstract : 889

PDF : 45
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DOI : 10.52340/gs.2025.07.04.49