Ключевые слова
essential oil
phenolic compounds
biological activity
Как цитировать
Аннотация
A study of the chemical composition of the essential oil obtained from the aerial parts of Salvia verticillata L., growing in Georgia, was carried out. The percentage of dominant components was determined by internal integration, the dominant component in the essential oil obtained from the leaves is caryophyllene (10.15 %), spathulenol (9.8 %), valeranone (11.9 %), and in the essential oil obtained from the flowers, germacrene D (17.2 %), caryophyllene (9.43 %). The ratio of terpene compounds was determined in the leaves and flowers of Salvia verticillata L., oxygenated sesquiterpenes are 38.43 % and 23.48 % respectively, and sesquiterpene hydrocarbons are 28.03 % and 40.61 %. The content of phenolic compounds was determined using Folin-Ciocalteu reagent in the aqueous, methanol and chloroform fractions of the residual plant material. The methanolic and chloroform fractions showed anti-inflammatory activity, the methanolic fraction – 100 % and the chloroform fraction – 83 % inhibiting the production of NO from lipopolysaccharide-stimulated mouse macrophage cells (RAW264.7). The aqueous fraction showed antioxidant activity (6.7 ± 0.3 micromole TE/mg) in the ORAC test.
Библиографические ссылки
რევაზ გაგნიძე, მურმან დავითაძე, ადგილობრივი ფლორა. ბათუმი, 2006.
დავლიანიძე მ., ღვინიაშვილი ც., მუყბანიანი მ., ჯიჯოლია-იმნაძე ლ., ჯუღელი თ., საქართველოს ფლორის ნომენკლატურული ნუსხა. თბილისი, 2018.
თეონა კორკოტაძე, დალი ბერაშვილი, ვახტანგ მშვილდაძე, მალხაზ გეთია, ალიოშა ბაკურიძე, “გვარი - სალბის, საქართველოში მოზარდი ზოგიერთი სახეობის, ქიმიური შემადგენლობა და ანტიოქსიდანტური აქტივობა,” ექსპერიმენტული და კლინიკური მედიცინა, no. 5–6, 2021.
Nurhayat Tabanca, Betül Demirci, Zeki Aytaç, K. Hüsnü Can Başer, “The chemical composition of Salvia verticillata L. subsp. verticillata from Turkey,” Nat. Volatiles & Essent. Oils, vol. 4(1), pp. 18–28, 2017.
M. Sharifi-Rad et al., “Salvia spp. plants-from farm to food applications and phytopharmacotherapy,” Trends in Food Science & Technology, vol. 80, pp. 242–263, Oct. 2018, doi: 10.1016/j.tifs.2018.08.008.
J. S. Katanić Stanković et al., “Bioactivity, biocompatibility and phytochemical assessment of lilac sage, Salvia verticillata L. (Lamiaceae) - A plant rich in rosmarinic acid,” Industrial Crops and Products, vol. 143, p. 111932, Jan. 2020, doi: 10.1016/j.indcrop.2019.111932.
MURAT TOSUN, SEZAI ERCISLI, MEMNUNE SENGUL, HAKAN OZER and TASKIN POLAT and ERDOGAN OZTURK, “Antioxidant Properties and Total Phenolic Content of Eight Salvia Species from Turkey,” Biol Res, vol. 42, pp. 175–181, 2009.
BAHMAN NICKAVAR, MOHAMMAD KAMALINEJAD AND HAMIDREZA IZADPANAH, “IN VITRO FREE RADICAL SCAVENGING ACTIVITY OF FIVE SALVIA SPECIES,” Pak. J. Pharm. Sci., vol. 20 (4), pp. 291–294, 2007.
V. Mihailović et al., “Green Synthesis of Silver Nanoparticles Using Salvia verticillata and Filipendula ulmaria Extracts: Optimization of Synthesis, Biological Activities, and Catalytic Properties,” Molecules, vol. 28, no. 2, p. 808, Jan. 2023, doi: 10.3390/molecules28020808.
საქართველოს ფლორა, vol. XI. თბილისი: მეცნიერება, 1987.
S. Karakaya et al., “A caryophyllene oxide and other potential anticholinesterase and anticancer agent in Salvia verticillata subsp. amasiaca (Freyn & Bornm.) Bornm. (Lamiaceae),” Journal of Essential Oil Research, vol. 32, no. 6, pp. 512–525, Nov. 2020, doi: 10.1080/10412905.2020.1813212.
Magda COISIN, Ioan BURZO, Marius ŞTEFAN, Elida ROSENHECH, Maria and Magdalena ZAMFIRACHE, “CHEMICAL COMPOSITION AND ANTIBACTERIAL ACTIVITY OF ESSENTIAL OILS OF THREE SALVIA SPECIES, WIDESPREAD IN EASTERN ROMANIA,” Analele Ştiinţifice ale Universităţii „Al. I. Cuza” Iaşi s. II a. Biologie vegetală, pp. 51–58, 2012.
C. Giuliani et al., “Salvia verticillata: Linking glandular trichomes, volatiles and pollinators,” Phytochemistry, vol. 155, pp. 53–60, Nov. 2018, doi: 10.1016/j.phytochem.2018.07.016.
Milica Aćimović, Biljana Kiprovski, Milica Rat, Vladimir Sikora, Vera Popović, Anamarija Koren, Milka Brdar-Jokanović, “Salvia sclarea: CHEMICAL COMPOSITION AND BIOLOGICAL ACTIVITY,” Journal of Agronomy, Technology and Engineering Management, vol. 1 (1), 2018.
Afsaneh Tavassoli, Akbar Esmaeili, Mohammad Ali Ebrahimzadeh, Shila Safaeyan, Mohamad Akbarzade and Abdolhossein Rustaiyan, “Chemical Composition of Essential Oil and Antibacterial Activity of Salvia Glutinosa L. Growing Wild in Iran,” Journal of Applied chemical Researches (JACR), vol. 3, no. 10, 2009.
Это произведение доступно по лицензии Creative Commons «Attribution-NonCommercial-NoDerivatives» («Атрибуция — Некоммерческое использование — Без производных произведений») 4.0 Всемирная.
Copyright (c) 2023 GEORGIAN SCIENTISTS