1.5 Pharmacology, Toxicology, and Pharmaceutics 

Concept for creating sunscreen cosmetics

UV - protective activity solar radiation ultraviolet visible infrared organic acids

Authors

The article examines a number of compounds with UV protective activity. Literature data on the use of organic synthetic compounds, mainly benzophenones, including dioxybenzone, sulisobenzone, oxybenzone and avobenzone, as well as cinnamates, salicylates, and PABA derivatives are described. It has been shown that, along with UV-protective activity, they also have side effects that are very harmful to the body. It is more advisable to use natural organic compounds. The possibility of using free fatty acids, their mono- and diglycerides and triglycerides is discussed in detail and justified. They contain certain amounts of lipids, carotenoids, flavonoids, polyphenols, phospholipids, free sterols, tocopherols and tocotrienols, triterpene alcohols, hydrocarbons, carotenoids, fat-soluble vitamins and a number of other compounds that exhibit activity against solar radiation. A similar effect is also considered when using essential oils oils. Along with similar activity, oils are used as promoters of the penetration of active substances through the skin and stratum corneum. When acids are applied to the skin, its permeability increases and the content of certain substances contained in medicinal and cosmetic forms for topical use increases in the lower layers of the skin. The data presented indicate the advisability of using organic acids.

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