STUDY OF ALKALOIDS FROM THE SPECIES Mahonia bealei (FORT.) CARR. INTRODUCED IN GEORGIA
Keywords:Alkaloids, berberine, liquid-liquid extraction, Mahonia, anti-inflammatory
The aim of the work was to study the introduced plant on the Black Sea coast of Adjara Mahonia bealei (Fort.) Carr. for the content of alkaloids. A comparative analysis of the quantitative yield of the total amounts of alkaloids isolated from the aerial organs of M. bealei, collected in the phase of active flowering, showed the advantage of the amount obtained from flowers - 2.48%. Based on the results of the HPLC analysis, it was concluded not only about the percentage of the main protoberberine and aporphine alkaloids, but also in which fractions, which alkaloid is dominant (in leaves, three bases dominate at once: berberine (27%), jatrorrhizine (23%), magnoflorin (18%), in branches and flowers - dominated by one base - berberine (50%) and palmatin (57%), respectively, the rest are present in the form of traces). The results of the preliminary investigation suggest that the alkaloid containing substances obtained from the aboveground vegetative organs of the plant demonstrate antioxidant and anti-inflammatory activities.
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