DEVELOPMENT OF LC-MS METHOD FOR DETERMINATION OF THE QUETIAPINE IN HUMAN URINE
PDF

How to Cite

Sivsivadze, K., Jokhadze, M., Tushurashvili, P., Murtazashvili , T., & Imnadze, N. (2021). DEVELOPMENT OF LC-MS METHOD FOR DETERMINATION OF THE QUETIAPINE IN HUMAN URINE. Collection of Scientific Works of Tbilisi State Medical University, 50, 95–97. Retrieved from https://journals.4science.ge/index.php/CSW/article/view/42

Abstract

Introduction Quetiapine (QT)– dibenzothiazepine derivative, is an atypical antipsychotic agent which is widely used in the treatment  of schizophrenia, bipolar mania and other psychotic disorders. Chemical it is2-(2-(4-dibenzo[b,f][1,4]thiazepine11-yl-1-piperazinyl)ethoxy)ethano ( Figure 1). Quetiapine was developed by  Astra Zenecaand approved by the FDA in 1997

PDF

References

Schizophrenia and other psychotic disorders, Georgian national recommendation for clinical practice, Tbilisi, Order of the Ministry of Labor, Health and social affairs of Georgia, 18.12.2008, #277/O, pg.41 2. Scott M. at all. Seroquel XR® (quetiapine fumarate)for Major Depressive Disorder (MDD) or Generalized Anxiety Disorder (GAD), AstraZeneca Pharmaceuticals LP Introduction and Background on Quetiapine, 08.04.2009, pg 5

European Pharmacopoeia 8 Edition, 2014, 07/ 2014:2541, pg. 4091-4093 th

Prescribing Information of SEROQUE, AstraZeneca, 2013, 10. 2013, 3262703 6/16, pg.1-19

Disposition of Toxic Drugs and Chemicals in Man, Fifth Edition RANDALL C. BASELT, Chemical Toxicology Institute Foster City, California CHEMICAL TOXICOLOGY INSTITUTE FOSTER CITY, CALIFORNIA, 1999, p.759-760.

Lindsay Murray, Frank Daly, Mark Little, Mike Cadogan, Toxicology Handbook, Second edition, 3.65 Quetiapine, 2011 Australia, pg.328-321

Fathalla Belal, Amina Elbrashy, Manal Eid & Jenny Jeehan Nasr, Stability Indicating HPLC Method for the Determination of Quetiapine: Application to Tablets and Human Plasma, Journal of Liquid Chromatography & Related Technologies, Volume 31, 2008 - Issue 9, pg. 1283-1298

Sara A. Bellomarinoa, Allyson J. Browna, Xavier A. Conlana, b, Neil W. Barnetta; Preliminary evaluation of monolithic column high-performance liquid chromatography with tris(2,22 -bipyridyl)ruthenium(II) chemiluminescence detection for the determination of quetiapine in human body fluids, Talanta, Volume 77, Issue 5, 15 March 2009, pg. 1873– 1876

Biljana Nigovi, Josipa Spaji, A novel electrochemical sensor for assaying of antipsychotic drug quetiapine, Talanta, Issue 86, 22 September 2011, pg. 393–399

Extractive Spectrophotometric Determination of Quetiapine Fumarate in Pharmaceuticals and Spiked Human Urine

A summary of “Uromics: Metabolomics in Urine for Seroquel®, Latuda®, and Haldol®”

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...