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Abstract
Vine and its products have been one of the most widely used medical products in traditional medicine since ancient times. Vine products have a complex composition, they are rich in biologically active substances with different therapeutical activities. The high nutritional and medicinal value of products of vine origin necessitates routine safety control, which includes the assessment of the content of various xenobiotics, including residual pesticides. Within the framework of this experiment, the optimal conditions for the quantitative and qualitative analysis methods of cypermethrin and penconazole residues in Georgian vine shoots were developed. For the isolation of cypermethrin and penconazole QuEChERS extraction was developed, which ensures rapid and efficient extraction of both target substances, individually and in combination (within 91-93%), and GC-MS method was used for quantitative and qualitative analysis of pesticides. Based on validation method has shown linearity (Cypermethrin R 2 =0.9982, Penconazole R 2 =0.9977), selectivity, low limit of detection and quantification, accuracy and precision.