EPIDERMOLYSIS BULLOSA – CLINICAL CASE

Аннотация

Inherited epidermolysis bullosa is a rare group of genetic diseases characterized by skin fragility and blistering on the skin and mucous membranes in response to minimal trauma. EB is generally classified into four types as follows: simplex EB with blisters within the epidermis; dystrophic epidermolysis bullosa (DEB) - below the basement membrane; junctional EB with blisters in the epidermal dermal junction, and Kindler syndrome with blisters at multiple levels of the skin. Cutaneous involvement varies from localized to widespread blistering depending on subtype. Extracutaneous involvement varies from none to severely debilitating or lethal. The oropharynx, trachea, esophagus, eyes, teeth, nails, hair can be involved depending on subtype. The article presents three cases of different types epidermolysis bullosa, in 4 month, 4 years, 30 years old patients.