THE ROLE OF VITAMIN D IN THE COURSE AND DEVELOPMENT OF SOME NEUROLOGICAL SYNDROMES
DOI:
https://doi.org/10.52340/jecm.2022.06.31Keywords:
Vitamin D, neurological syndromes, developmentAbstract
Over the past decade, many reports addressed the importance of vitamin D in the development of neurological, neurodegenerative and mental diseases. Nevertheless, there are many controversial and unresolved problems, contradictory opinions and data. The aim of the study was to determine the importance of vitamin D deficiency in the development and course of some neurological syndromes in children and adolescents. 150 patients aged 1 to 16 years were studied. According to the clinic, they were divided into following groups: A - mild mental and speech delay (17 patients); В - behavioral disorder (18); B1 - autistic spectrum disorder (13); C - Attention Deficit Hyperactivity Disorder (17); D - frequent headache (24); E - fatigue (19); F - insomnia (23); G - seizures (19). The research resulted in a couple of conclusions: 40% of patients with attention deficit hyperactivity disorder had got significantly lower levels of Vitamin D in each age group. Administering vitamin D (Aquadetrim) during 2.5 months reduced hyperactivity, aggression, improved memory and speech skills. 38% of patients with epilepsy who had been taking antiepileptic drugs for more than 3 years had low levels of vitamin D in their blood (11.4 to 16.5 ng / ml). However, prescribing high doses of vitamin D in combination with anticonvulsants might develop side effects, which makes it necessary to control vitamin D level during treatment. Low levels of vitamin D (13,4-18.8 ng / ml) were found in 28% of practically healthy children aged 6 to 16 years (control group). A detailed study of the anamnesis revealed frequent fatigue, periodic headaches, insomnia. Vitamin D deficiency has an important role in the pathogenesis of somatic and as well as neurological diseases, and its deficiency is difficult to diagnose due to polysymptomatic clinical manifestations, we consider it necessary to include vitamin D research in a routine (mandatory) analysis to determine its role in both acute and chronic diseases.
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