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The goal of this work was to study the impact of chick- en’s liver thermostable protein complex immobilized in neutral ointment on the proliferation of the homologous cells. It was shown, that using neutral hydrocarbon ointment as a delivery implement for the protein complex, does not cause the change of leucocytes’ total number in the peripheral blood. The Chicken’s TPC immobilized in neutral hydrocarbon ointment reaches the body and has an inhibitory effect on hepatocytes’ mitotic activity in adolescent rats’ liver. Based on the above data and possible positive results after analogous research on model system of vessels, it may be recommended to use neutral hydrocarbons ointment as an effective delivery method of cell proliferation regulating protein factors. The obtained data may be the basis for future preclinical studies.
წყაროები
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