How to Cite

Chincharadze, S., Vadachkoria, . Z., & Mchedlishvili, . I. (2021). TERRITORIAL DISTRIBUTION OF CLEFT LIP AND PALATE IN GEORGIA. Collection of Scientific Works of Tbilisi State Medical University, 50, 133–135. Retrieved from https://journals.4science.ge/index.php/CSW/article/view/54


Territorial distribution of cleft lip and palate was studied in the regions of Georgia on the basis of the data for 20062015. During the analyzed period frequency of these malformations was 0.95+0.04 per 1000 live birth. They were unevenly distributed in the territory of Georgia. Most intensively they occurred in the regions of the East Georgia, where prevalence (without Tbilisi) composed 1.71/1000 that is quite high rate. These anomalies were especially widely spread in Mtskheta-Mtianeti region, where the rate was reaching 2.25/ 1000. In the West and South Georgia as well as in Tbilisi, cases of cleft lip and palate were much less. In the West Georgia rate of this pathology was no more than 0.70/1000, in Tbilisi – 0.80/1000 and in the South Georgia – 0.89/1000 respectively. Identification of reasons of uneven distribution of cleft lip and palate will have practical implication for their prevention in future.



Негаметзянов Н. Г., Супиев Т.К. Экологические факторы различных регионов Республики Казахстан и их влияние на заболеваемость врожденной расщелиной верхней губы и неба. Стоматология детского возраста и профилактика, 2012, №1 (40), с 41-48, 2012, ¹1 (40), ñ 41-48

Butali A., Adeyemo W.L., Mossey P.A. et al. Prevalence of orofacial clefts in Nigeria. Cleft Palate Craniofac.J., 2014, 51(3): 320-325

Jalilevard N., Jalaie S. Prevalence of cleft lip and palate among four provinces in the West and North-West of Iran. J. Res. Med. Sci., 2015, 20(6):548-553

Kelly D., O’ Dowd T., Reulbach U. Use of folic acid supplements and risk of cleft lip and palate in infants: a population-based cohort study. Br.J. Gen. Prac., 2012, 62(600):e 466-472

Lin Y., Shu S., Tang S. A case-control study of environmental exposures for nonsyndromic cleft of the lip and/ or palate in eastern Guangdong, China. Int. J. Otorhinolaryngol., 2014, 78(3):544-550

Mossey P.A., Little G., Munger R.G, et al. Cleft lip and palate. Lancet., 2009 374(9703):1773-1785

Murray J.C. Gene/Environment causes of cleft lip and/ or palate. Clin.Genet., 2002, 61 (4):248-256

Panamonta V., Pradubwong S., Panamonta M.,Chowchuen B. Global birth prevalence of orofacial clefts: a systematic review. J. Med. Assoc. Thai., 2015, 98, Suppl. 7:S11-21

Tanaka S.A., Mahabir R.C., Jupiter D.C., Menezes J.M. Updating the epidemiology of cleft lip with or without cleft palate. Plast.reconstr.Surg, 2012, 129(3):511-518


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