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Abstract
The European Lycopus (Lycopus europaeus L.) belongs to Lamiaceae family. It is a perennial herbaceous plant. It contains various chemical constituents: phenol carbonic acids, essential oils, tannins, flavonoids, mineral substances. Medicinal plant is widespread in Europe, West Asia and the eastern part of North America. Lycopus europaeus L. is growing in Georgia, in particular -Adjara, Kartli, Samegrelo and Guria regions.
The European Lycopus is used in folk medicine for the treatment of coughs, respiratory system, gastrointestinal tract, thyroid diseases. It is the best sedative for anxiety and insomnia. Preclinical pharmacological studies have established the antithyroid, antimicrobial, antioxidant, antiparasitic, anti-inflammatory, analgesic activity of medicinal plant. Lycopus europaeus L. growing in Georgia is not studied well.
The aim of the research was investigation of the pharmacognostic study of the Lycopus europaeus L. growing in Georgia. Was identified morphological features and peculiarities of anatomical structure by macroscopic and microscopic analysis of crud drug of Lycopus europaeus L. Were detected 55 and identified 26 substances in ethanolic extract by chromatographic methods. Phenol carbolic acids: caffeinic acid, rosmarinic acid, ferulic acid, vanillic acid, p-coumaric acid, salicylic acid, benzoic acid, 4-0-caffeoylquinic acid; Flavonoids: quercetin, kaempferol-3-rutinoside, catechin, chrysin, naringenin. Monoterpenes: citral, p-menthane; Sesquiterpenes: á-acorenol, caryophyllene, â-bourbonene, ethyladamantan, â-guaiene, longipinocarveol, isolongifolol. pyranone, 5-methoxypyrrolidin, benzofuranone, phytol. Were determined some quality parameters: moisture content 10.2%, total ash 8%, extractive substances 27.0%, tannins 7% and rosmarinic acid content 2.3%.