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Sweet Syndrome (also known as acute febrile neutrophilic dermatosis) is typically characterized by the acute onset of pyrexia and painful cutaneous lesions that are composed of a densedermal inflammatory infiltrate of mature neutrophils. Neutrophilia is also frequently present. Both the condition -associated symptoms and the dermatosis-related lesions promptly resolve after initiation of treatment with systemic corticosteroids.
Dr. Robert Douglas Sweet, originally described acute febrile neutrophilic dermatosis in the August-September 1964 issue of the British Journal of Dermatology. He summarized the cardinal features of “a distinctive and fairly severe illness” that had been encountered in 8 women during the 15-year period from 1949 to 1964. IN Dr. Sweet’s department, the condition was originally referred to as the Gomm- Button disease “in eponymous honor of the first two patients” with the disease. Subsequently, this acute febrile neutrophilic dermatosis has become best known by the eponym “Sweet syndrome”
The prevalence of the disease is up to 9 cases per 1 million people. Scientific publications include describe several hundred cases of Sweet’s syndrome [2].