How to Cite
ცისკარიშვილი ნ. T. N., კაციტაძე ა. K. A., ცისკარიშვილი ნ. T. N., ცისკარიშვილი ც. T. T., & ჭითანავა ლ. C. L. (2019). PERSPECTIVE OF PHOTOTHERAPY OF DERMATOSES BY MEANS OF UVB -311 NM. Collection of Scientific Works of Tbilisi State Medical University, 49, 141–143. https://doi.org/10.52340/csw.2015.49.0.141-143
Abstract
The paper presents the modern data concerning the spectrum of electromagnetic radiation and its impact on the structure and function of the skin at various dermatoses. The possibilities of non-drug treatment of dermatoses using different UV spectrum are described. Particular attention is paid to the study of the most effective and safe method for treatment by means of narrow-wave phototherapy with a maximum emission at a wavelength of 311 nm (UVB - 311). The results of the comparative analysis of efficacy and safety of PUVA photochemotherapy and phototherapy UVB -311, on examples of some specific nosologic units (psoriasis, parapsoriasis, vitiligo, mycosis fungoides, photodermatosis, atopic dermatitis) are presented. Based on analysed data, authors conclude that UVB -311 nm is an effective, well-tolerated, safe and alternative method for treatment of chronic dermatoses. The brief review of the available in literature data, allow authors to make conclusion about the possibility of widespread implementation of phototherapy method in practical dermatology.
References
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2. Doghin NN, Hassan AM, EI - Ashmawy AA et al Topical Antioxydant and Nerrowband versus Topical combination of Calcipotriol plus Betamethazone Dipropionate and Narrowband in the Treatment of Vitiligo. Life Sci J 2011 ; 8; 186 -197
3. Akdeniz N., Yavuz IH,Gunes Bilgili S et al Comparison of efficacy of narrow band UVB therapies with UVB alone, in combination with calcipotriol, and with batametazone and calcipotriol in vitiligo. J Dermatol Treat 2014; 25; 196 -199
4. Kalafi A, Jowkar F. Efficacy of Topical Tetracycline in Enhancing the Effect of Narrow Bamd UVB agoinst Vitiligo. A Double –Blind, Randomized placebo –Controlled Clinical Trial. ISRN Dermatol 2014; 201‘472 -546
5. Bansal S,Sahoo B, Garg V. Psoralen - narrowband UVB phototherapy for the treatment of vitiligo in comparison to narrowband UVB alone Photodermatol Photoimmunol Photomed 2013; 29; 311 -317
6. Grimes PE, Hamzavi I,Lebwohl M, Ortonne JP, Lim HW. The efficacy the afamelanotide and narrowband UV-B phototherapy for repigmentacion of vitiligo JANA Dermatol 2013; 149;68 -73
7. Weatherhead SC, Farr PM, Jamision D et al Keratinocyte apoptosis in epidermal remodeling and clearance of psoriasis indeced by UV radiation J,Invest Drrmatol 2011,131, 1916 -1926
8. Gambichler T., Terras S., Skrygan M. Cycloogenase 2 expression and apoptosis in normal and psoriatic epidermis models exposed to salt water soaks and narrowband ultraviolet B radiation JEADV 2015,1,180 -183
9. Chun KS., Langenbach R The prostaglandin E2 receptor,,EP2 regulates surviving expression via an EGFR / STAT3 pathway in UVB exposed mouse skin Mol Carcinog, 2011, 50,439 – 448
10. Gambichler T., Terras S., Skrygan M TGFâ/ Smad signaling in psoriatic epidermis models to salt water soaks and narrowband ultraviolet B radiation Cytokine 2013, 64, 35 -38
11. Cho TH, Lee JW, Lee MH Evaluating the cytotoxic dozes of narrowband and broadband UVB in human keratinocytes, melanocytes and fibroblasts Photodermatol. Photoimmunol Photomed 2008 ; 24; 110 -114
12. Baron ED, Stevens SR. Phototerapy for cutaneous T – cell lymphoma. Dermatol Ther 2003 : 16: 303 -310
13. Friedland, David M, Feinmesser M et al NB –UVB (311 -312 nm) - induced lentigines in patient with mycosis fungoi des : a new adverse effect of photot herapy JEADV,2012,9, 1158 -1163
14. Furua R, Yoshida Moro O et al Immunihistochemi- cal survey of the distribution of melanoblasts and melanocites during development of UVB –induced pigmented spots J Dermatol Sci 2009; 55; 99 -107
15. Otsuka A, Miyachi Y, Kabashima K Narrowband ul- traviolet B pho totherapy decreased the serum IL – 17 level in patients with psoriasis vulgaris JEADV, 2012, 11, 1455 1456
16. Tintle S, Shemer A, Suarez - Farinas M et al Reversal of atopic dermatitis with narrow – band UVB phototherapy and biomarkers for therapeutic response J Allergy Clin Immunol 2011: 128: 583 -593
17. Johnson – Huang LM, Suarez Farinas M, Sullivan – Whalen M et al Effective narrow – band UVB radiation therapy suppresses the IL - 23/ IL – 17 axis in normalized psoriasis plagues J invest Dermatol ôîòî2010, 130: 2654 – 2663
18. Rlein A, Schiffner R,Shiffner –Rohe J, Einsele- Kramer B et al A randomized clinical trial in psoriasis : synchronous balmeopphototherapy with bathing in Dead Sea salt solution plus narrowband UVB vs narrowband UVB alone JEADV 2011,5< 570 -579
19. Олисова О.Ю., Микрюков А.В., Верхатурова Е.Г. Фототерапия узкого спектра 311 нм в лечении различных дерматозов Рос.журн кож.. вен боле¬зней 2008, 5, 52-58.
20.Суворова А.П., Жаркокова Е.Е., Богомолова Н.В Фототерапия витилиго. Рос журн кож и вен болезней 2008,5, 81 – 83. 21.Богадельникова Ф.Е., Олисова О.Ю., Вла¬димирова В,В. Микрюков А.В. Лечение больных атопическим дерматитом с применене селекти¬вной фототерапии УФ - лучами 311 нм. Рос. журн. кож.вен. бол., 2007,2, 30 -3
2. Doghin NN, Hassan AM, EI - Ashmawy AA et al Topical Antioxydant and Nerrowband versus Topical combination of Calcipotriol plus Betamethazone Dipropionate and Narrowband in the Treatment of Vitiligo. Life Sci J 2011 ; 8; 186 -197
3. Akdeniz N., Yavuz IH,Gunes Bilgili S et al Comparison of efficacy of narrow band UVB therapies with UVB alone, in combination with calcipotriol, and with batametazone and calcipotriol in vitiligo. J Dermatol Treat 2014; 25; 196 -199
4. Kalafi A, Jowkar F. Efficacy of Topical Tetracycline in Enhancing the Effect of Narrow Bamd UVB agoinst Vitiligo. A Double –Blind, Randomized placebo –Controlled Clinical Trial. ISRN Dermatol 2014; 201‘472 -546
5. Bansal S,Sahoo B, Garg V. Psoralen - narrowband UVB phototherapy for the treatment of vitiligo in comparison to narrowband UVB alone Photodermatol Photoimmunol Photomed 2013; 29; 311 -317
6. Grimes PE, Hamzavi I,Lebwohl M, Ortonne JP, Lim HW. The efficacy the afamelanotide and narrowband UV-B phototherapy for repigmentacion of vitiligo JANA Dermatol 2013; 149;68 -73
7. Weatherhead SC, Farr PM, Jamision D et al Keratinocyte apoptosis in epidermal remodeling and clearance of psoriasis indeced by UV radiation J,Invest Drrmatol 2011,131, 1916 -1926
8. Gambichler T., Terras S., Skrygan M. Cycloogenase 2 expression and apoptosis in normal and psoriatic epidermis models exposed to salt water soaks and narrowband ultraviolet B radiation JEADV 2015,1,180 -183
9. Chun KS., Langenbach R The prostaglandin E2 receptor,,EP2 regulates surviving expression via an EGFR / STAT3 pathway in UVB exposed mouse skin Mol Carcinog, 2011, 50,439 – 448
10. Gambichler T., Terras S., Skrygan M TGFâ/ Smad signaling in psoriatic epidermis models to salt water soaks and narrowband ultraviolet B radiation Cytokine 2013, 64, 35 -38
11. Cho TH, Lee JW, Lee MH Evaluating the cytotoxic dozes of narrowband and broadband UVB in human keratinocytes, melanocytes and fibroblasts Photodermatol. Photoimmunol Photomed 2008 ; 24; 110 -114
12. Baron ED, Stevens SR. Phototerapy for cutaneous T – cell lymphoma. Dermatol Ther 2003 : 16: 303 -310
13. Friedland, David M, Feinmesser M et al NB –UVB (311 -312 nm) - induced lentigines in patient with mycosis fungoi des : a new adverse effect of photot herapy JEADV,2012,9, 1158 -1163
14. Furua R, Yoshida Moro O et al Immunihistochemi- cal survey of the distribution of melanoblasts and melanocites during development of UVB –induced pigmented spots J Dermatol Sci 2009; 55; 99 -107
15. Otsuka A, Miyachi Y, Kabashima K Narrowband ul- traviolet B pho totherapy decreased the serum IL – 17 level in patients with psoriasis vulgaris JEADV, 2012, 11, 1455 1456
16. Tintle S, Shemer A, Suarez - Farinas M et al Reversal of atopic dermatitis with narrow – band UVB phototherapy and biomarkers for therapeutic response J Allergy Clin Immunol 2011: 128: 583 -593
17. Johnson – Huang LM, Suarez Farinas M, Sullivan – Whalen M et al Effective narrow – band UVB radiation therapy suppresses the IL - 23/ IL – 17 axis in normalized psoriasis plagues J invest Dermatol ôîòî2010, 130: 2654 – 2663
18. Rlein A, Schiffner R,Shiffner –Rohe J, Einsele- Kramer B et al A randomized clinical trial in psoriasis : synchronous balmeopphototherapy with bathing in Dead Sea salt solution plus narrowband UVB vs narrowband UVB alone JEADV 2011,5< 570 -579
19. Олисова О.Ю., Микрюков А.В., Верхатурова Е.Г. Фототерапия узкого спектра 311 нм в лечении различных дерматозов Рос.журн кож.. вен боле¬зней 2008, 5, 52-58.
20.Суворова А.П., Жаркокова Е.Е., Богомолова Н.В Фототерапия витилиго. Рос журн кож и вен болезней 2008,5, 81 – 83. 21.Богадельникова Ф.Е., Олисова О.Ю., Вла¬димирова В,В. Микрюков А.В. Лечение больных атопическим дерматитом с применене селекти¬вной фототерапии УФ - лучами 311 нм. Рос. журн. кож.вен. бол., 2007,2, 30 -3
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