THE STUDY OF THE POSSIBILITY OF THERAPEUTIC APPLICATION OF IMMOBILIZED IN NEUTRAL OINTMENT OF THE PROTEIN FACTOR INHIBITING CELL PROLIFERATION
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How to Cite

Ghibradze, G., Gunia, V., Bakuridze, A., Modebadze, I., Dzidziguri, L., Dzidziguri, D., & Vadachkoria, Z. (2020). THE STUDY OF THE POSSIBILITY OF THERAPEUTIC APPLICATION OF IMMOBILIZED IN NEUTRAL OINTMENT OF THE PROTEIN FACTOR INHIBITING CELL PROLIFERATION. Collection of Scientific Works of Tbilisi State Medical University, 54, 155–158. Retrieved from https://journals.4science.ge/index.php/CSW/article/view/1940

Abstract

The goal of this work was to study the impact of chick- en’s liver thermostable protein complex immobilized in neutral ointment on the proliferation of the homologous cells. It was shown, that using neutral hydrocarbon ointment as a delivery implement for the protein complex, does not cause the change  of  leucocytes’ total number in the  peripheral blood. The Chicken’s TPC immobilized in neutral hydrocarbon ointment reaches the body and has an inhibitory effect on  hepatocytes’  mitotic activity  in adolescent  rats’  liver. Based on the above data and possible positive results after analogous research on model system of vessels, it may be recommended to use neutral hydrocarbons ointment as an effective delivery method of cell proliferation regulating protein factors. The obtained data may be the basis for future preclinical studies.

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