CHRONIC PLAQUE PSORIASIS – CLINICAL CASE

Authors

SALOME KHIMSHIASHVILI Tbilisi State Medical University
MERI KAKAURIDZE Tbilisi State Medical University
IRINA MUSERIDZE Tbilisi State Medical University
MARIAMI DAVLASHERIDZE Tbilisi State Medical University
ALEXANDER KATSITADZE Tbilisi State Medical University
NATO KORSANTIA Tbilisi State Medical University

DOI:

https://doi.org/10.52340/jecm.2026.02.16

Keywords:

Psoriasis, Plaque Psoriasis, Immune-Mediated Disease, Chronic Dermatosis

Abstract

Psoriasis is a chronic autoimmune inflammatory skin condition characterized by recurring red, scaly patches. Its development involves a complex interaction between T lymphocytes, dendritic cells and proinflammatory cytokines, especially IL-23, IL-17 and TNF- α. Typical histopathological features include: acanthosis, parakeratosis, Munro microabscesses, dilated capillaries in the dermal papillae and thinning of the skin above the papillae. This article describes the case of a 48-year-old woman with chronic plaque psoriasis, presenting with widespread red, scaly lesions on her back, elbows, buttocks and lower legs. Large, merging plaques on her sacral and gluteal areas were especially noticeable, showing thickened skin, superficial cracks and lichenification – signs of a longstanding inflammatory process.

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Author Biographies

SALOME KHIMSHIASHVILI, Tbilisi State Medical University

Tbilisi State Medical University, Department of Dermatology and Venereology; Tbilisi, Georgia

MERI KAKAURIDZE, Tbilisi State Medical University

Tbilisi State Medical University, Department of Dermatology and Venereology; Tbilisi, Georgia

IRINA MUSERIDZE, Tbilisi State Medical University

Tbilisi State Medical University, Department of Dermatology and Venereology; Tbilisi, Georgia

MARIAMI DAVLASHERIDZE, Tbilisi State Medical University

Tbilisi State Medical University, Department of Dermatology and Venereology; Tbilisi, Georgia

ALEXANDER KATSITADZE, Tbilisi State Medical University

Tbilisi State Medical University, Department of Dermatology and Venereology; Tbilisi, Georgia

NATO KORSANTIA, Tbilisi State Medical University

Tbilisi State Medical University, Department of Dermatology and Venereology; Tbilisi, Georgia

References

DermNet NZ. Chronic plaque psoriasis. https://dermnetnz.org/topics/chronic-plaque-psoriasis

Wolff K., Johnson R.A., Saavedra A.P., Roh E.K. Fitzpatrick’s Color Atlas and Synopsis of Clinical Dermatology. 8th ed. McGraw-Hill Education; 2017:50–61.

Elmets C.A., Leonardi C.L., Davis D.M.R., et al. Joint AAD-NPF guidelines of care for the management and treatment of psoriasis with awareness and attention to comorbidities. J Am Acad Dermatol. 2019;80(4):1073–1113.

American Academy of Family Physicians. Psoriasis: Guidelines for management. https://www.aafp.org/afp/2006/0215/p636

Feldman S.R. Chronic plaque psoriasis in adults: Overview of management. UpToDate. https://www.uptodate.com/contents/chronic-plaque-psoriasis-in-adults-overview-of-management

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Published

2026-06-02

How to Cite

KHIMSHIASHVILI, S., KAKAURIDZE, M., MUSERIDZE, I., DAVLASHERIDZE, M., KATSITADZE, A., & KORSANTIA, N. (2026). CHRONIC PLAQUE PSORIASIS – CLINICAL CASE. Experimental and Clinical Medicine Georgia, (2), 96–98. https://doi.org/10.52340/jecm.2026.02.16

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