Phytochemical and Biological Study of the Leaves of Yucca Elephantipes Regel.
Downloads
The aim of the research was to study the phytochemical properties of the leaves of Yucca elephantipes Regel, introduced to Georgia and to determine its pharmacological efficacy.
The composition of the total extract obtained from the leaves of the plant has been studied; the qualitative and quantitative content of substances using spectral analysis methods has been determined; and the pharmacological activity of the total extract has been evaluated.
In the total extract of Yucca elephantipes Regel. leaves furostanol glycosides with a content of 26.42% were determined; As a result of the study of the qualitative composition of sapogenins of leaves, the dominant genins were determined: smilagenin, tigogenin, diosgenin and gecogenin;
Antioxidant activity of the total extract obtained from Y. elephantipes leaves was studied by DPPH and ABTS reagents in vitro. According to the results of the DPPH reagent, the study object has an average antioxidant activity (56.2 ± 0.4), and according to the results of the ABTS reagent, the study object has a high antioxidant activity (6.9 ± 0.2).
Downloads
1. Физер Л., Физер М., Стероиды.- М.: Мир, 1964., 982
2. Кемертелидзе Э.П., Пхеидзе Т.А. Стероидные соединения некоторых растений, произрастающих в Грузии. 1999, Мецниереба, 184
3. Камерницкий А.В., Абубакиров Н.К., Горовиц М.Б., Воллернер Ю.Е., Войшвилло Н.Е.,. Решетова И.Г, Пасешниченко В.А. . Химия спиростанолов. М.: Наука, 1986, 176
4. Schmiedeberg O. Untersuchungen uber die pharmacologischwirksamen bestandteile der Digitalis purpurea L. Archiv of experimental pathology and Pharmacology. 1875, N3. 16-19
5. Кемертелидзе Э.П., Бенидзе М.М., Схиртладзе А.В., Надараиа Н.Ш., Мерлани М.И., Амиранашвили Л.Ш. Синтез стероидных гормональных препаратов из тигогенина интродуцированной в Грузии Yucca gloriosa и изучение химического состава растения. Тбилиси, 2018, 230
6. Karamova N., Gumerova S., Hassan G., Abdul-Haffez E., Ibrahim O. Orabi,A. Linskaya. Antioxidant and antimutagenic potential of some species of Agavaceae family plants. Bionanoscience 2016, 6, 591-593
7. EquiarteL.E., Leebens M., Heiduk K. Editorial: Recent advances and future perspectives for Agavoideae research: Agave, Yucca and related taxa, Frontiers in Plant Science, 2021, 12, 687 596.
8. Кинтя П.К., Лазуревский Г.В., Балашова И.И. и др. Строение и биологическая активность стероидных гликозидов ряда спиростана и фуростана. Кишинев, Штиинца, 1987, 141
9. Одишария К.Ю. Главнеишие вечнозеленные покрытосеменные растения Черноморского побережья Кавказа. Изд. АН ГССР, 1959, 361
10. Bernier G.R., Ethnobotany of the northen cheyonne: medicinal plants. Master thesis, University of Montana Missoula, USA, 2004.
11. Cordele G.A. Phytochemistry and traditional medicine. Phytochemistry letters, 2011, 4, 391-398
12. Lim T.K., Lim, T.K. Yucca Filamentosa. Edible Medicinal and Non-Medicinal Plants. Flowers, 2014, 7, 134–137
13. Ying Zhanga, Chong-Ren Yanga, Ying-Jun Zhang, New Steroidal Saponins from the Leaves of Yucca elephantipes, Helvetica Chimica Acta, 2013, V. 96, Is. 9, 1807-1813.
14. Naida Juárez-Trujillo, Juan Luis Monribot-Villanueva, Víctor Manuel Jiménez-Fernández, Rosaelena Suárez-Montaño, Ángel Sahid Aguilar-Colorado, José Antonio Guerrero-Analco, Maribel Jiménez, Phytochemical characterization of Izote (Yucca elephantipes) flowers, Journal of Applied Botany and Food Quality, 2018, 91, 202-210
15. Kemertelidze E., Benidze M., Nebieridze V., Skhirtladze A., Ganzera M., Chemical composition of flowers of Yucca elephantipes Regel. cultivated in Georgia., Chemistry of Natural Compounds, 2020, V. 56, N. 5, 874-877
16. Zhang, Y., Zhang, Y.J., Jacob, M.R., Li, X.C., Yang, C.R. Steroidal saponins from the stem of Yucca elephantipes. Phytochemistry, 2008, 69, 264–270
17. Oleszek W., Sitek M., Stochmal A., Piacente,S., Pizza C.,Cheeke P., Resveratrol and other phenolics from the bark of Yucca schidigera. Journal of the Agricultural and Food Chemistry, 2001, 49, 747–752
18. Kedare SB., Singh RP.. Genesis and development of DPPH method of antioxidant assay. J Food Sci Technol. 2011, 48(4):412-22.
19. Etsè KS., Etsè KD., Nyssen P., Mouithys-Mickalad A. Assessment of anti-inflammatory-like, antioxidant activities and molecular docking of three alkynyl-substituted 3-ylidene-dihydrobenzo[d]isothiazole 1,1-dioxide derivatives. Chem Biol Interact. 2021, 1;344:109513
20. Re, R.; Pellegrini, N.; Proteggente, A.; Pannala, A.; Yang, M.; Rice-Evans, C. Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Rad. Biol. Med. 1999, 26, 1231–1237
21. Ilyasov IR., Beloborodov VL., Selivanova IA., Terekhov RP.. ABTS/PP Decolorization Assay of Antioxidant Capacity Reaction Pathways. International Journal of Molecular Sciences. 2020; 21(3):1131
Copyright (c) 2026 Georgian Scientists
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
