THE CLINICAL-EPIDEMIOLOGICAL CHARACTERIZATION OF COVID-19 AND ASSOCIATED CONCOMITANT DISEASES IN GEORGIA

Abstract

On 11 March the World Health Organization (WHO) declared the COVID-19 a pandemic [2]. From the moment of the first cases to 23 September 2020, more than 31 million people were confirmed with the virus, and more than 971,000 deaths have occurred due to the disease

This paper analyzes the epidemiological and clinical data, as well as concomitant diseases of 130 patients with laboratory-confirmed COVID 19.  The aim of the study is also re- veal patients who may develop critical illness by COVID- GRAM predictive risk score.

From 130 patients 82[63.1%] were hospitalized in the first three days from the onset of the disease. The average age of patients is 48 years, the maximum is 86 years. Patients were divided into 3 clinical groups: I - COVID 19 without lung damage - 40 [30.7%], II - with lung damage - 75 [57.7%], III - critical 15 [11.5%]. Died 7 [lethality 5.4%]. In critically ill patients was the highest rate of comorbidities of Arterial hypertension, CVD, Diabetes.

It is worth to mention that initially, according clinical symptoms in the stage of viral replication stage there was no significant difference between groups. The frequency of comorbidities was increased along with the age. According to COVID-GRAM calculator, prediction of development of critical illness was easy in patients with mild and high risk. Most of the patients were found in Gray zone where the risk of developing critical illness is moderate. Thus, there should be done further studies for identification new prediction markers of critical illness.