კეტოგენური დიეტის ახალი პრესპექტივები
DOI:
https://doi.org/10.52340/jecm.2022.06.20საკვანძო სიტყვები:
ketogenic diet, ketomolecules, metabolic healthანოტაცია
კეტოსხეულების კლინიკურმა ეფექტურობამ თანდათანობით დიდი აღიარება მოიპოვა. ამ მიმოხილვითი სტატიის მიზანია, აჩვენოს, რომ კეტოსხეულები განიხილება, როგორც არა მხოლოდ ენერგიის ალტერნატიული წყარო შიმშილისა და დაბალნახშირწყლოვანი დიეტების დროს, არამედ, როგორც სასიგნალო მოლეკულები. აღმოჩნდა, რომ ისეთ სახეობებში, როგორებიცაა თაგვები, ვირთხები, თევზები, ჭიები, ბუზები და სხვა, დაბალკალორიული დიეტები მნიშვნელოვან როლს თამაშობს სიცოცხლის გახანგძლივებისა და ასაკთან ასოცირებული დავადებების შეჩერების პროცესში. კეტოგენური დიეტის ფონზე წარმოქმნილი კეტომოლეკულები წარმოადგენს ჩვენი ორგანიზმის მეტაბოლური ჯანმრთელობისა და სიცოცხლის გახანგძლივების მნიშვნელოვან მარეგულირებელ ნივთიერებას, რომლებიც ბევრი, ჯერ კიდევ უცნობი მოლეკულური მექანიზმით ამსუბუქებს ფენოტიპის დაბერების პროცესს, მოდულაციას უკეთებს ლიპოლიზს, ენერგიის ხარჯვას, ცვლის მეტაბოლიზმის სიჩქარეს, ინსულინის მიმართ რეზისტენტობას, ზემოქმედებს აუტოფაგიის პროცესებზე.
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