INFLAMMATORY SYNDROMES ASSOCIEATED WITH SARS-COV-2 IN PEDIATRIC PATIENTS: A CASE SERIES

INFLAMMATORY SYNDROMES ASSOCIEATED WITH SARS-COV-2 IN PEDIATRIC PATIENTS: A CASE SERIES

Authors

  • EKA NAKHUTSRISHVILI
  • IRINE KEKELIDZE
  • MANANA KOBAKHIDZE
  • TINATIN KUTUBIDZE

DOI:

https://doi.org/10.52340/jecm.2025.01.16

Keywords:

Sars-CoV2, inflammatory syndromes, pediatric patients

Abstract

In the wake of the COVID-19 pandemic, an increasing number of pediatric cases with prolonged febrile syndromes, multi-system involvement, and hyperinflammatory features have emerged. This article presents a series of four pediatric cases with diverse presentations of persistent inflammatory states, exploring their clinical course, diagnostic challenges, and management strategies.

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References

Riphagen, S., Gomez, X., Gonzalez-Martinez, C., Wilkinson, N., & Theocharis, P. (2020). Hyperinflammatory shock in children during COVID-19 pandemic. The Lancet, 395(10237), 1607-1608.

Verdoni, L., Mazza, A., et al. (2020). An outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic: an observational cohort study. The Lancet, 395(10239), 1771-1778.

Canna, S. W., & Behrens, E. M. (2012). Making sense of the cytokine storm: a conceptual framework for understanding, diagnosing, and treating hemophagocytic syndromes. Pediatric Clinics of North America, 59(2), 329-344.

Seneviratne, U., Gunawardena, N., & de Silva, N. R. (2022). The association between post-infectious triggers and autoimmune diseases: A comprehensive review. Autoimmunity Reviews, 21(1), 102901.

Whittaker, E., Bamford, A., Kenny, J., et al. (2020). Clinical characteristics of 58 children with a pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2. JAMA, 324(3), 259-269.

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Published

2025-02-27

How to Cite

NAKHUTSRISHVILI, E., KEKELIDZE, I., KOBAKHIDZE, M., & KUTUBIDZE, T. (2025). INFLAMMATORY SYNDROMES ASSOCIEATED WITH SARS-COV-2 IN PEDIATRIC PATIENTS: A CASE SERIES. Experimental and Clinical Medicine Georgia, (1), 89–90. https://doi.org/10.52340/jecm.2025.01.16

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