PROGNOSTIC SIGNIFICANCE OF IL-6 IN STILLBIRTH DURING COVID 19 PANDEMIC

NATIA PKHALADZE; NIKOLOZ KINTRAIA; NINO GOGOKHIA; KHATIA MIKABERIDZE

doi:10.52340/jecm.2023.05.09

PROGNOSTIC SIGNIFICANCE OF IL-6 IN STILLBIRTH DURING COVID 19 PANDEMIC

Authors

NATIA PKHALADZE
NIKOLOZ KINTRAIA
NINO GOGOKHIA
KHATIA MIKABERIDZE

DOI:

https://doi.org/10.52340/jecm.2023.05.09

Keywords:

Prognostic significance, IL-6, Stillbirth, COVID 19

Abstract

The pro inflammatory cytokine IL-6 was studied by the method of immune-ferment analysis (IFA) in the blood serum in women with stillbirth during COVID infection. 3 patients suffering from this complication were examined (the principal group) and 25 patients - of adequate age groups and gestation periods but live fetuses in both groups presented SARS COV 2 infection which was confirmed with laboratory PCR (Polymerase Chain Reaction) test. The result of studies showed that the content of proinflammatory cytokine IL-6 in women with antenatal fetal death was significantly higher in the blood than in patients with normal progress of pregnancy. The obtained data prove that further studies of cytokine profile and especially of IL-6 may become an important method for the prognosis for stillbirth during SARS COV 2 pandemic period.

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