Аннотация
Myopia is a rising problem in modern ophthalmology. Its progression and a number of related complications are one of the main causes of irreversible vision loss and blindness worldwide. Dependence on smartphones, computers, and other electronic devices makes myopia the leading cause of visual impairment in children. The development of optical coherence tomography-angiography (OCTA) provided a non-invasive method of examining the morphological changes of large and small blood vessels, which allows the examination of the density of the retina and choriocapillaris of near-sighted children in correlation with the axial axis, in order to determine the expected pathological changes developed during myopia. The purpose of the study is to measure the density of retinal layers and choriocapillaris, as well as evaluation of the thickness of these tissues through optical-coherence tomography-angiography and determine its relationship with the anterior-posterior axis of different eye sizes in myopic children. 96 eyes of 48 myopic subjects and 40 eyes of 20 emmetropic volunteers were examined. The spherical equivalent of myopes was greater than -1.0 D. For emmetropes, from +0.5 to 0.5 D; The length of the axial axis is 24.58mm (SD±1.22) and 22.88mm (SD±0.65). Patients aged 7-16, who were also involved in the study, underwent a complete ophthalmological examination. Retinal and choriocapillaris density were examined using SS-OCTA DRI Triton. According to the results of the study, the density of superficial retinal blood vessels is lower in myopic eyes than in emmetropic eyes and correlates with the axial axis. In patients with medium and high myopia, the choroid is significantly thinner than in patients with low-grade myopia; Also, there is a decrease in the density of choriocapillaris in patients with moderate and high myopia in the upper and lower segments, but not in the nasal and temporal regions. Obviously, it is very important to carry out long-term observations of such patients in terms of determining microvascular changes in the future.
Библиографические ссылки
Oxidative Stress in myopia. franciso, Bosch-morell. s.l.:Hindawi, 2015, Hindawi, p. 12.
Association between retinal microvasculature and optic disc alterations in high myopia. Chen, J. H. Q. 2019.
Association between optic nerve head deformation and retinal microvasculature in high myopia. sung, T. h. l. Misun. 2018.
Optical coherent tomography-angiography of peripapillary retinal blood flow response to hyperoxia. Pechauer, Y.J. D. H. Alex D.
Myopia: anatomic changes and consequences for its etiology. Jonas,. K. o.-m. S. P.-J. Jost b.
Myopia, axial length and oct charasteristics of the macula in Singaporean children. Luo,. H. 2016.
Assotiation between optic nerve heas deformation and retinal microvasculature in high myopia. Sung., T. H. L. MiSun. 2018.
In vivo mapping of the choriocapillaris in high myopia a wildfield ss-octa. masterpaqua,. P. V. E. B. Rodolfo. 2019.
A comparison of enhanced depth imaging oct of chorioidal thickness between different oct device. Hua, D. X. Siya.
Opticl coherence tomography-angiography of superficial retinal vessel density and foveal avascular zone in myopic children. Golebiewska,. K. B.-G. Joanna. 2019.
Reduced macular vascular density in myopic. Fan H,Chen HY, Ma HJ, Chang Z, Yin HQ, Ng DS. 2017, Chin Med,pp. 445-451.
Retinal microvascular network and microcirculation assessments in high myopia. Li M, Yang Y, Jiang H, Gregori G, Roisman L, Zheng F.
Quantitative OCT Angiography of the retinal microvasculature and the choriocapillaris in Myopic Eyes. AlSheikh M, hasukkijwatana N, Dolz-Marco R, Rahimi M, Iafe NA, Freund KB.
Vascular flow density in pathological myopia: an optical coherence tomography angiography study. Mo J, Duan A, Chan S, Wang X, Wei W.
Morphological changes of choriocapillaris in experimentally induced chick myopia. Hirata A, Negi A. 1998.
Vessel density, retinal thickness, and choriocapillaris vascular fow in myopic eyes on OCT angiog-raphy. Milani P, Montesano G, Rossetti L, Bergamini F, Pece A. 2018.
Retinal and choroidal thickness in myopic anisometropia. Vincent SJ, Collins MJ, Read SA, Carney LG.
Myopic anisometropia: ocular characteristics and aetiological considerations. Vincent SJ, Collins MJ, Read SA,Carney LG.
Quantitative OCT angiography of the retinal microvasculature and the choriocapillaris in myopic eyes. Al-Sheikh M, Phasukkijwatana N, Dolz-Marco R, Rahimi M, Iafe NA, Freund KB,.
all Changes in choroidal thickness varied by age and refraction in children and adolescents: a 1-year longitudinal study. Xiong S, He X, Zhang B, Deng J, Wang J, Lv M,.
Longitudinal changes in choroidal thickness and eye growth in childhood. Read SA, Alonso-Caneiro D, Vincent SJ, Collins MJ.
Optical coherence tomography angiography for the assessment of choroidal. Devarajan K, Sim R, Chua J, Wong CW, Matsumura S, Htoon HM.
MJ. Wide-feld choroidal thickness and vascularity index in myopes and emmetropes. Yazdani N, Ehsaei A,Hoseini-Yazdi H, Shoeibi N, Alonso-Caneiro D, Collins MJ.
Increased choroidal blood perfusion can inhibit form deprivation myopia in guinea pigs. Zhou X, Zhang S, Zhang G, Chen Y, Lei Y, Xiang J,.
Scleral hypoxia is a target for myopia control. Wu H,Chen W, Zhao F, Zhou Q, Reinach PS, Deng L,.