THE INFLUENCE OF AGE, SEX AND ANTHROPOMORPHIC PARAMETERS ON SUBSETSOF LYMPHOCYTES IN GEORGIA'S POPULATION
PDF (English)

Как цитировать

Lasareishvili, B., Pantsulaia, N., Iobadze, M., Kikodze, N., Pantsulaia, I., & Chikovani , T. (2013). THE INFLUENCE OF AGE, SEX AND ANTHROPOMORPHIC PARAMETERS ON SUBSETSOF LYMPHOCYTES IN GEORGIA’S POPULATION. Сборник научных трудов ТГМУ, 47, 103–107. извлечено от https://journals.4science.ge/index.php/CSW/article/view/1974

Funding data

Аннотация

Changes in immune system have crucial role in the process of organism’s ageing. Immune senescence is closely linked to age-associated diseases, such as chronic diseases and cancer. Revealing influence of impact factors on immune senescence has theoretical and practical importance. There are different pattern of immune senescence under different environmental conditions. Therefore, it is important to study it in populations that live under different geoclimatic conditions and belonging to different ethnic groups.

The 250 health volunteers from Georgia’s population were investigated. We studied percentage of lymphocytes subsets in the peripheral blood and evaluated influence of age, sex and anthropomorphic parameters on them.

Lymphocytes quantitative data fluctuated in different periods of age. No significant relation was revealed between percentage content of lymphocytes’ subsets and anthropomorphic parameters.

PDF (English)

Библиографические ссылки

Amadori A, Zamarchi R, De SG, Forza G, Cavatton G, Danieli GA, Clementi M, Chieco-Bianchi L: Genetic control of the CD4/CD8 T-cell ratio in humans. Nat Med 1995, 1:1279-1283.

Balistreri CR, Candore G, Accardi G, Bova M, Buffa S, Bulati M, Forte GI, Listi F, Martorana A, Palmeri M, et al: Genetics of longevity. data from the studies on Sicilian centenarians. Immun Ageing 2012, 9(1) :8.

Beagley KW, Gockel CM: Regulation of innate and adaptive immunity by the female sex hormones oestradiol and progesterone. FEMS Immunol Med Microbiol 2003, 38(1):13 - 22.

Beatriz Garcia Verdecia, Danay Saavedra Hernandez, Patricia Lorenzo-Luaces et al. Imunosenescence and gender: a study in healthy Cubans, Immunity & Ageing 2013, 10:16.

Bisset L.R., Lung T.L., Kaelin M. et al. Reference values for peripheral blood lymphocyte phenotypes applicable to the healthy adult population in Switzerland. Eur J Haematol 2004;(3) 203-212.

Bouman A, Schipper M, Heineman MJ, Faas MM: Gen-der difference in the non-specific and specific immune response in humans. Am J Reprod Immunol 2004, 52:19-26.

Carmichael KF, Abayomi A: Analysis of diurnal vari-ation of lymphocyte subsets in healthy subjects in the Carib-bean, and its implication in HIV monitoring and treatment. Afr J Med Med Sci 2006, 35:53-7.

Das BR, Bhanushali AA, Khadapkar R, Jeswani KD, Bhavsar M, Dasgupta A: Reference ranges for lymphocyte subsets in adults from western India: influence of sex, age and method of enumeration. Indian J Med Sci 2008, 62:397-406.

Dorshkind K, Swain S: Age-associated declines in immune system development and function: causes, consequences, and reversal. Curr Opin Immunol 2009, 21(4):404 - 407.

Garcia-Dabrio M.C., Pujol-Moix b, Martinez-Perez A.: Influence of Age, Gender and Lifestyle in Lymphocyte Subsets: Report from the Spanish Gait-2 Study, Acta Haematol 2012;127:244-249.

Hince M, Sakkal S, Vlahos K, Dudakov J, Boyd R, Chidgey A: The role of sex steroids and gonadectomy in the control of thymic involution. Cell Immunol 2008, 252(1 - 2):122 - 138.

Jentsch-Ullrich K, Koenigsmann M, Mohren M, et al. Lymphocyte subsets’ reference ranges in an age- and gender-balanced population of 100 healthy adults - A mono- centric German study. Clin Immunol. 2005;116:192-197.

Jiang W, Kang L, Lu HZ, et al: Normal values for CD4 and CD8 lymphocyte subsets in healthy Chinese adults from Shanghai. Clin Diagn Lab Immunol 2004, 11:811-3.

Krause D, Mastro AM, Handte G, et al. Immune function did not decline with aging in apparently healthy, wellnourished women. Mech Ageing Dev. 1999;112:43-57.

Lee BW, Yap HK, Chew FT, et al: Age- and sex-related changes in lymphocyte subpopulations of healthy Asian subjects: from birth to adulthood. Cytometry 1996, 26:8-15.

Madhuri R Thakar, Philip R Abraham, Sunil Arora, Establishment of reference CD4+ T cell values for adult Indian population, AIDS Research and Therapy 2011, 8:35.

McCarthy M: The “ gender gap ” in autoimmune disease. Lancet 2000, 356(9235):1088.

Messele T, Abdulkadir M, Fontanet AL, Petros B, Hamann D, Koot M, Roos MT, Schellekens PT, Miedema F, Rinke de Wit TF: Reduced naive and increased activated CD4 and CD8 cells in healthy adult Ethiopians compared with their Dutch counterparts. Clin Exp Immunol 1999; 115: 443-450.

Скачивания

Данные скачивания пока недоступны.