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Аннотация
The present study was conducted to determine the re-lease of the drug substances of various natures from softdosage forms. The study was conducted using the Franzdiffusion cell approach. Chicken comb skin, a newborn ratskin biopsy (taken from the abdomen), polyethylene, andeggshell membranes were used as the membrane model. Thestudy subjects were salicylic acid, rutin and protein. Thediffusion rate of the drugs was determined in the phosphatebuffer area (pH 7.4) at 37 ± 0.5° C temperature for 12 hours.The concentrations of salicylic acid and rutin retained bythe membranes used in the diffusion process were deter-mined at the end of the study (after 12 hours). The experi-mental studies have shown that the rate of diffuse process-es in the rat skin is higher compared to the chicken combskin. In addition, maximum retention of active pharmaceuti-cal ingredients was observed in chicken comb skin. Minimaldrug retention was observed in polyethylene and eggshellmembrane samples.Библиографические ссылки
ღიბრაძე გ., გუნია ვ., ბაკურიძე ა., მოდებაძე ი., ძიძიგური ლ., ძიძიგური დ., & ვადაჭკორია ზ. (2020). ნეიტრალურ მალამოში იმობილიზირებული უჯრედების გამრავლების მაინჰიბირებელი ცილოვანი ფაქტორის თერაპიული მიზნით გამოყენების შესაძლებლობის შესწავლა . თბილისის სახელმწიფო სამედიცინო უნივერსიტეტის სამეცნიერო შრომათა კრებული, 54, 155–158. Retrieved from https://journals.4science.ge/index.php/CSW/article/view/1940
Uttam Budhathoki, Mail Kshitij Gartoulla, Shailendra Shakya.Formulation and evaluation of transdermal patches of atenolol. Indonesian J. Pharm. 2016. Vol. 27 No. 4 : 196 – 202
Navneet Kumar Verma, Anubha Gupta, Harendra Pras- ad, Vikash Chandra. Formulation and Evaluation of Trans- dermal Patches Containing Paracetamol. International Jour- nal of Chemistry and Pharmaceutical Sciences. 2014, Vol.2(4): 774-776.
P.Palanisamy, B.Jaykar, B.S.Venkateswarlu, R.Margret Chandira, and Suriyan. D. A Review on Transdermal Drug Delivery System. Indian Journal of Natural Sciences. Vol.10 / Issue 61 / August / 2020. P.1-22.
Ramesh Y., Anjana A, Karunasree M., Manjula Devi B., Sankeerthana K., Sri Lakshmi P.,Va-s-a-nthi A.Formulation and Evaluation of Atenolol Transdermal Patches. Cre. J. Pha. Res. 2015.1(2) 55-65.
Shelke Usha Y.* , Mahajan Ashish A. Review on: an Ointment. Ijppr.Human, 2015; Vol. 4 (2): 170-192.
Viral Shah, Sanjay Raval, Sapna Peer, U.M. Upadhyay. A comparative evalution of different membranes for their diffusion efficiency: an in vitro study. An international jour- nal of pharmaceutical sciences. Vol-1, Issue-2, 2010. P.41-49.
Woo Yeup Jeong, Mina Kwon, Hye Eun Choi and Ki Su Kim. Recent advances in transdermal drug delivery sys- tems: a review. BiomaterialsResearch(2021) 25:24. P.1-15.
Jung HL. Update on infantile hemangioma. Clin Exp Pediatr. 2021 Nov;64(11):559-572.
Дзидзигури Д.В., Иобадзе И.Р., Асламазишвили Т.Т., Туманишвили Г.Д., Бахуташвили В.И., Чигогидзе Т.Г., Манагадзе Л.Г. “Сравнительное изучение влияния эндогенных почечных факторов на пролиферативную активность эпителиоцитов”, Цитология, 2005, 47(6): 497-500.
Leung AKC, Lam JM, Leong KF, Hon KL. Infantile Hemangioma: An Updated Review. Curr Pediatr Rev. 2021;17(1):55-69.