EVALUTION OF FUNCTIONALCAPACITY AND EXERCISE TOLERANCEIN PATIENTS WITH HEART FAILUREAND HYPERURICEMIA

Аннотация

The aim of our study was to assess physical activitytolerance with a 6-minute walk test and assess quality of lifeusing the Minnesota Questionnaire in patients with heartfailure (HF) with or without hyperuricemia. Materials andmethods: we studied 126 patients with heart failure: 75 (59.5%)had hyperuricemia, the control group consisted of 51 (40.4%)patients with HF who did not have hyperuricemia. To com-pare the data, we studied 30 people aged 60-68 who did nothave HF. We assessed exercise tolerance with a 6-minutewalk test (6-MWT) and assessed quality of life using theMinnesota Quality of Life Questionnaire. Comparison of theresults showed that the difference between the results of the6-MWT in functional classes II was not statistically signifi-cant, but was a significant difference in classes III and IV.Also, there was a significant difference between patientswith hyperuricemia and without hyperuricemia patients in allfunctional class groups. So, the increase in NYHA function-al class is closely correlated with a decrease in 6-MWT scoresin all groups of patients. A quality-of-life study showed thatthe first group of patients had more pronounced discomfortand deterioration in quality of life predominantly during phys-ical activity (paragraphs 3,4,9,12). Also, patients in this grouphad a higher rate of 13,14,19,20,21 points. So, a decrease inexercise tolerance and quality of life is observed in all pa-tients with HF, although these changes are more pronouncedin patients with hyperuricemia. Conclusion: The 6-MWT isan easily performed test and is reliably correlated with func-tional classes of HF in both hyperuricemia and without hy-peruricemia patients. The Minnesota Quality of Life Score isa reliable marker of HF severity in patients with hyperuricam-ia.