THE NECESSITY OF REDUCING THE SURGICAL INTERVENTIONS ON THE REGIONAL ZONES OF METASTASIZING IN EARLY BREAST CANCER (REVIEW)

Abstract

Reducing the amount of surgical interventions on the axillary region is the logical continuation of the modern understanding of breast cancer natural history. Article shortly describes the results from NSABP B-32, IBCSG 23-01, AATRM, ACOSOG Z0011, EORTC 10981-22023 AMAROS, MA.20, SENTINA (SENTinel NeaoAdjuvant), SN FNAC and ACOSOG Z1071 randomized trials, which became bases for recommendations of the 16th St. Gallen International Conference, ESMO and renewed 2019 NCCN practice guidelines.