Abstract
Seborrheic pemphigus is an overlap syndrome with features of lupus erythematosus and seborrheic dermatitis, consequently, its’ differential diagnosis is complicated. Our aim is to present characteristic clinical features of seborrheic pemphigus. Rapid assessment and starting pulse therapy with systemic glucocorticoids is essential because seborrheic pemphigus tends to transform into pemphigus foliaceus and sometimes an outcome can be fatal for the patients. We present a clinical case of a 60-year-old patient. He complained about the rash, which appeared on his face, chest and upper back. Subjective complaints were pain and burning sensation in affected areas. Objective findings were: on erythematous base were notable flaccid bullae and eroded lesions covered with dark colored crusts. After the crust removal, wet surfaces appeared. Secondary hyperpigmentation was remarkable in areas, where erosions were already epithelialized. At the site of lesions, Nickolsky sign was positive. Complete blood cell count and urinalysis were within normal limits. The cytologic pattern was characterized by acantholysis.
References
ა.კაციტაძე. დერმატოლოგია და ვენეროლოგია 2020. თავი მე-18. ერითმული ბუშტოვანა.
Sewon KAang, Masayuki Amagai, Anna L. Bruckner, Alexander H. Enk, David J. Margolis, Amy J. McMichael, Jeffrey S. Orringer. Fitzpatrick’s Dermatology, Ninth Edition,1-Volume. Pp.914.
Hertl M. Autoimmune diseases of the skin. Pathogenesis, diagnosis, management. 3rd Ed. Springer Wien New York, 2011. p. 593.