Nowadays, it is actual to develop technological-organizational systems for resource-efficient and secondary use of herbal raw materials. Studies have shown that grape origin products, rich with polyphenols, reduce chronic inflammatory processes (by modulating inflammation pathways or decreasing the active oxygen level). Studies have also confirmed the antibacterial and antioxidant activity of extracts from grape origin products. it is noteworthy that more than 500 types of grape varieties are common in Georgia, and winemaking is one of the common industries, the average amount of grapes processed annually is 100,000 tons, although no winemaking waste processing enterprises have been created. Based on the above, the waste of grape processing products and its processing organization are of great importance. It is important to study the wine lees obtained from different varieties of grape in Georgia, which averages 5,000 tons per year. The purpose of this review article is to create the appropriate interest to make it possible to identify the waste product of wine production (wine lees) as a new, natural source. This has scientific and economic significance, since it will develop new approaches to obtaining biologically active substances: it will create a prerequisite for the currently accumulated products of viticulture and winemaking to be used as a natural resource of biologically active substances.
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