Abstract
Nowadays, it is actual to develop technological-organizational systems for resource-efficient and secondary use of herbal raw materials. Studies have shown that grape origin products, rich with polyphenols, reduce chronic inflammatory processes (by modulating inflammation pathways or decreasing the active oxygen level). Studies have also confirmed the antibacterial and antioxidant activity of extracts from grape origin products. it is noteworthy that more than 500 types of grape varieties are common in Georgia, and winemaking is one of the common industries, the average amount of grapes processed annually is 100,000 tons, although no winemaking waste processing enterprises have been created. Based on the above, the waste of grape processing products and its processing organization are of great importance. It is important to study the wine lees obtained from different varieties of grape in Georgia, which averages 5,000 tons per year. The purpose of this review article is to create the appropriate interest to make it possible to identify the waste product of wine production (wine lees) as a new, natural source. This has scientific and economic significance, since it will develop new approaches to obtaining biologically active substances: it will create a prerequisite for the currently accumulated products of viticulture and winemaking to be used as a natural resource of biologically active substances.
References
Cushnie, TPT, Lamb, AJ. Antimicrobial activity of flavonoids. International Journal Of Antimicrobial Agents 2005;26: 343-356.
Egert S., Rimbach G., Which Sources of Flavonoids:Complex Diets or Dietary Supplements?, Advances in Nutrition, vol.2, 2011, pp. 8-14
Furiga, A.; Lonvaud-Funel, A.; Badet, C. In vitro study of antioxidant capacity and antibacterial activity on oral anaerobes of a grape seed extract. Food Chem. 2009, 113, 1037-
https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=celex%3A52007DC0575Commission Of The European Communities, Communication From The Commission To The
European Parliament, The Council, The European Economic And Social Committee And The Committee of the Regions,Brussels, 10.10.2007
Korkina, L., Kostyuk, V.; de Luca, C.; Pastore, S. Plant phenylpropanoids as emerging anti-inflammatory agents.Mini Rev. Med. Chem. 2011, 11, 823-835
Park, J.; Park, J.H.; Suh, H.J.; Lee, I.C.; Koh, J.; Boo,Y.C. Effects of resveratrol, oxyresveratrol, and their acetylated derivatives on cellular melanogenesis. Arch. Dermatol.
Res. 2014, 306, 475-487.
Rosch, D.; Bergman, M,; Knorr, D.; Kroh, L.W. Structure antioxidadant efficiency relationships of phenoliccompounds and their contribution to antioxidant acticity of sea
buckthorn juice. J. Agric. Food Chem. 2003, 51, 4233-4239
Sema C., Baydar N.B Osman Sagdic O., Ozkan G., .,Determination of antibacterial effects and total phenolic contents of grape (Vitis vinifera L.) seed extracts, International
Journal of Food Science & Technology Volume 41, Issue 7
Sousa E.C., Athayde A.M, Beserra J.O., Selene Maia de MORAIS S.A., Alessandro de LIMA A., Clécio Galvão MARTINS C., et all, Chemical composition and bioactive
compounds of grape pomace (Vitis vinifera L.), Food Science and Technology, Food Sci. Technol, Campinas, 34(1):135-142, Jan.-Mar. 2014
Zhijing Y., Shavandi A.1, Harrison R., Bekhit A.E.,Characterization of Phenolic Compounds in Wine Lees, Antioxidants 2018, 7(4), 48