Harmful effects of pharmaceutical pollution on the environment and its consequences
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Keywords

Pharmaceutical contamination
water contamination
antimicrobial resistance
anomalies
infertility
disinfection by-products

How to Cite

Mazanashvili, V., & Kipshidze, M. (2023). Harmful effects of pharmaceutical pollution on the environment and its consequences. Junior Researchers, 1(1), 30–44. https://doi.org/10.52340/2023.01.01.04

Abstract

In the 21st century, the development of technology and science has brought with it polluting consequences. Quite a large share of them by the pharmaceutical industry There is pollution of the environment, mostly the hydrosphere, with various pharmaceutical products. Such an action may have serious consequences, such as provoking diseases in humans or animals, hormonal imbalance, development of bacterial resistance to antimicrobial agents, congenital ugliness. In this article several studies are discussed in order to present the relevance and threats of the topic both in today's reality and in the future perspective. The main emphasis was placed on the development of antimicrobial resistance and on such chemical pollutants that have teratogenic and reproductive function-disrupting effects on the human body. Also calling for finding ways to avoid pharmaceutical contamination, as there is currently no proper control to avoid such dire consequences. Environmental pollutants have a negative effect on human health. Pharmaceutical pollution takes one of the leading places in this regard. It is important to take appropriate preventive measures to avoid severe consequences of pollution.  In addition, many studies should be conducted to develop the technologies needed to avoid pollution.

https://doi.org/10.52340/2023.01.01.04
pdf

References

Andrews J., Nichols H., Schmid J., Mole L., Hunter E., Klinefelter G. Developmental toxicity of mixtures: The water disinfection by-products dichloro-, dibromo- and bromochloro acetic acid in rat embryo culture. Reprod. Toxicol. 2004;19:111–116. doi: 10.1016/j.reprotox.2004.06.005. [PubMed] [CrossRef] [Google Scholar]

Berger A, Ziv-Gal A, Cudiamat J, Wang W, Zhou C, Flaws JA. The effects of in utero bisphenol A exposure on the ovaries in multiple generations of mice. Reprod Toxicol. 2016 Apr;60:39-52. doi: 10.1016/j.reprotox.2015.12.004. Epub 2015 Dec 30. PMID: 26746108; PMCID: PMC4866900

Dodds L.A., King W. Relation between trihalomethane compounds and birth defects. Occup. Environ. Med. 2001;58:443–446. doi: 10.1136/oem.58.7.443.

Gonsioroski A, Mourikes VE, Flaws JA. Endocrine Disruptors in Water and Their Effects on the Reproductive System. Int J Mol Sci. 2020 Mar 12;21(6):1929. doi: 10.3390/ijms21061929. PMID: 32178293; PMCID: PMC7139484

Li S, Liu Z, Süring C, Chen L, Müller S, Zeng P. The Impact of the Antibiotic Fosfomycin on Wastewater Communities Measured by Flow Cytometry. Front Microbiol. 2022 Mar 3;12:737831. doi: 10.3389/fmicb.2021.737831. PMID: 35310391; PMCID: PMC8928225.

Martin, Jake M.; Saaristo, Minna; Bertram, Michael G.; Lewis, Phoebe J.; Coggan, Timothy L.; Clarke, Bradley O.; Wong, Bob B.M. (March 2017). "The psychoactive pollutant fluoxetine compromises antipredator behaviour in fish". Environmental Pollution. 222: 592–599.

OECD Studies on Water. Paris: OECD Studies on Water, OECD Publishing. 13 November 2019.

Smith R., Edwards S.C., Best N., Wright J., Nieuwenhuijsen M.J., Toledano M.B. Birth Weight, Ethnicity, and Exposure to Trihalomethanes and Haloacetic Acids in Drinking Water during Pregnancy in the Born in Bradford Cohort. Environ. Heal. Perspect. 2015;124:681–689. doi: 10.1289/ehp.1409480.

Yang P, Zeng Q, Cao WC, Wang YX, Huang Z, Li J, Liu C, Lu WQ. Interactions between CYP2E1, GSTZ1 and GSTT1 polymorphisms and exposure to drinking water trihalomethanes and their association with semen quality. Environ Res. 2016 May;147:445-52. doi: 10.1016/j.envres.2016.03.009. Epub 2016 Mar 10. PMID: 26970898.

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