IMMUNOREHABILITATION STRATEGY AND TACTICS IN PATIENTS AFTER SURGICAL OPERATIONS – A LITERATURE REVIEW

IMMUNOREHABILITATION STRATEGY AND TACTICS IN PATIENTS AFTER SURGICAL OPERATIONS – A LITERATURE REVIEW

Authors

  • NATO KAKABADZE
  • REVAZ SEPIASHVILI
  • TATIANA SLAVYANSKAYA
  • NERIMAN TSINTSADZE
  • MIKHEIL ARTMELADZE

DOI:

https://doi.org/10.52340/jecm.2026.01.08

Keywords:

immunorehabilitation, surgery, literature review

Abstract

This literature review examines the strategy and tactics of immunorehabilitation for patients following surgical operations. The modern lifestyle, characterized by chronic stress, poor nutrition, and environmental toxins, often leads to immunosuppression, increasing the risk of postoperative complications. The article traces the evolution of immunology from generalized immunotherapy to the modern concept of immunorehabilitation - a systematic, multidisciplinary approach aimed at restoring immune function to a physiological norm. A central focus is the three-stage model (clinical, ambulatory, and maintenance) that ensures comprehensive care. The review concludes that a personalized immunorehabilitation strategy is crucial for preventing complications, accelerating tissue regeneration, and achieving successful long-term outcomes in surgical patients.

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References

Immunology of Stress: A Review Article- Amna Alotiby, Editors: Margherita Sisto, Francesc Graus. J Clin Med. 2024 Oct 25;13(21):6394. doi: 10.3390/jcm13216394

Exposure to Environmental Toxins and Autoimmune Conditions - Datis Kharrazian. Integr Med (Encinitas). 2021 Apr;20(2):20–24.

Emotional Stress and Immune Response in Surgery: A Psychoneuroimmunological Perspective- Taufiqa Reza, Han Grezenko, Chad Barker, Danyal Bakht, Nuzhat Faran, Noor Abdullah Yahya, Maryam Affaf, Hana Mohamed, Rayan Gasim, Mohammed Khaleel IKH Almadhoun, Abdur Rehman, Uday Kumar, Abdullah Shehryar, Abdul Haseeb Hasan. 2023 Nov 13;15(11):e48727. doi: 10.7759/cureus.48727. eCollection 2023 Nov.

Prehabilitation Strategies: Enhancing Surgical Resilience with a Focus on Nutritional Optimization and Multimodal Interventions- Suriyaraj Shanmugasundaram Prema, Dhanraj Ganapathy, Deepankumar Shanmugamprema. Received 5 December 2024, Revised 24 January 2025, Accepted 12 February 2025, Available online 15 February 2025, Version of Record 13 March 2025. https://doi.org/10.1016/j.advnut.2025.100392

IMMUNOREHABILITOLOGY: A LOOK FROM THE SOURCES TO THE FUTURE. FROM IMMUNOTHERAPY TO PERSONALIZED TARGETED IMMUNOREHABLITATION- Revaz Sepiashvili May 2017 Georgian Medical News

Contemporary Concept of Immunorehabilitation- Revaz I. Sepiashvili 1999 Dec;4(4):319-321.

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Published

2026-03-14

How to Cite

KAKABADZE, N., SEPIASHVILI, R., SLAVYANSKAYA, T., TSINTSADZE, N., & ARTMELADZE, M. (2026). IMMUNOREHABILITATION STRATEGY AND TACTICS IN PATIENTS AFTER SURGICAL OPERATIONS – A LITERATURE REVIEW. Experimental and Clinical Medicine Georgia, (1), 59–61. https://doi.org/10.52340/jecm.2026.01.08

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