ASPECTS OF THE FEATURES OF CHALLENGES OF ANTIFUNGAL RESISTANCE, ISSUES OF MYCOTOXICOLOGY, MYCOECOLOGY AND PROBLEMS OF BIOLOGICAL SAFETY IN GENERAL

ASPECTS OF THE FEATURES OF CHALLENGES OF ANTIFUNGAL RESISTANCE, ISSUES OF MYCOTOXICOLOGY, MYCOECOLOGY AND PROBLEMS OF BIOLOGICAL SAFETY IN GENERAL

Authors

  • NODAR SULASHVILI Tbilisi State Medical University image/svg+xml
  • LUIZA GABUNIA Tbilisi State Medical University image/svg+xml
  • MARGARITA BEGLARYAN Yerevan State Medical University After Mkhitar Heratsi, Yerevan, Armenia
  • NANA GORGASLIDZE Tbilisi State Medical University image/svg+xml
  • MARINA GIORGOBIANI Tbilisi State Medical University image/svg+xml
  • NATIA KVIZHINADZE Tbilisi State Medical University image/svg+xml
  • NANA PEIKRISHVILI Tbilisi State Medical University image/svg+xml
  • MARIKA SULASHVILI Tbilisi State Medical University image/svg+xml
  • IRINE ZARNADZE Tbilisi State Medical University image/svg+xml
  • SHALVA (DAVIT) ZARDANDZE Tbilisi State Medical University image/svg+xml

DOI:

https://doi.org/10.52340/jecm.2025.04.14

Keywords:

Antifungal resistance, mycotoxicology, mycoecology, biological safety

Abstract

The article reviews key aspects related to Candida fungi, including their clinical significance, mechanisms of antifungal resistance, mycotoxicological risks, ecological prevalence, and biosafety challenges. Candida fungi are an important group of opportunistic pathogens that can cause a wide range of infections in immunocompromised hosts. Studying the mechanisms of Candida adaptation to various environments and their ability to form biofilms is important for understanding the pathogenesis and developing effective therapeutic strategies. In addition, antifungal resistance is becoming an increasingly pressing public health problem requiring new approaches in antimicrobial therapy. Studies of mycotoxicological aspects indicate the potential toxicity of some Candida metabolites and the need for their monitoring.

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Author Biography

NODAR SULASHVILI, Tbilisi State Medical University

Yerevan State Medical University After Mkhitar Heratsi, Yerevan, Armenia

References

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Sulashvili N, Davitashvili M, Gorgaslidze N, Gabunia L, Beglaryan M, Alavidze N, Sulashvili M. The scientific discussion of some issues of features and challenges of using of CAR-T cells in immunotherapy. Georgian Sci. 2024;6(4):263–90. doi:10.52340/gs.2024.06.04.24

Sulashvili N, Gorgaslidze N, Gabunia L, Giorgobiani M, Ratiani L. Manifestation of the particularities of the usage features of monoclonal antibodies in various pharmacotherapeutic applications. Exp Clin Med Georgia. 2023;(4):52–7. doi:10.52340/jecm.2023.04.14

Sulashvili N, Gorgaslidze N, Gabunia L. Manifestation of the particularities of some key issue aspects of new immunotherapy challenges and perspectives by CAR-T cell therapy. Exp Clin Med Georgia. 2024;(4):119–21. doi:10.52340/jecm.2024.04.32

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Published

2025-08-21

How to Cite

SULASHVILI, N., GABUNIA, L., BEGLARYAN, M., GORGASLIDZE, N., GIORGOBIANI, M., KVIZHINADZE, N., … ZARDANDZE, S. (DAVIT). (2025). ASPECTS OF THE FEATURES OF CHALLENGES OF ANTIFUNGAL RESISTANCE, ISSUES OF MYCOTOXICOLOGY, MYCOECOLOGY AND PROBLEMS OF BIOLOGICAL SAFETY IN GENERAL. Experimental and Clinical Medicine Georgia, (4), 52–55. https://doi.org/10.52340/jecm.2025.04.14

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