THE EFFECTIVENESS OF RAMAN SPECTROSCOPY AS A PROGNOSTIC MARKER DURING EXAMINATION OF WOMEN WITH INFLAMMATORY COMPLICATIONS IN THE POSTPARTUM PERIOD
Keywords:Raman Spectroscopy, prognosis, marker, postpartum, inflamation
The author studied the effectiveness of the Raman spectroscopy method as a prognostic marker in women with inflammatory complications in the postpartum process. 300 women were included in the study. 250 of these women had inflammatory complications during pregnancy, and they made up the main group. In the remaining 50 women, inflammatory complications were observed during the menstrual period, that is, they were practically healthy women and made up the control group. The blood samples of these women included in the study were analyzed using Raman spectroscopy. According the results of research the number of women with higher frequency was less, it was 19.2% in total, and in 107 women, the frequency indicator of blood serum spectrogram was less. From the obtained results, it was found that the frequency and intensity indicators were low in 50 women included in the control group. There were no differences between the 107 women in the main group with a low spectrogram frequency and the women in the control group, which indicates that they did not have an inflammatory process. The difference between women with low intensity index (n=107) and the control group (n=50) was not statistically significant (p=0.44828, p<0.05). Thus, there were general similarities in the spectrograms of the blood samples of patients who showed inflammatory complications during pregnancy.
Bergholt, M. S. et al. Characterizing variability of in vivo Raman spectroscopic properties of different anatomical sites of normal colorectal tissue towards cancer diagnosis at colonoscopy. Anal. Chem. 2015; 87:960–966.
Ember K.J., Hoeve M.A., McAughtrie S.L. et al. Raman spectroscopy and regenerative medicine: a review // Medicine, 2017; 2(12):1-10.
Talari, A. C. S., Movasaghi, Z., Rehman, S. & Rehman, I. U. Raman spectroscopy of biological tissues. Appl. Spectrosc. Rev. 2015; 50:46–111.