EFFECTS OF ORAL DEHYDROEPIANDROSTERONE (DHEA) SUPPLEMENTATION ON HORMONAL PROFILE AND MENOPAUSAL CLINICAL SYMPTOMS IN EARLY POSTMENOPAUSAL SYMPTOMATIC WOMEN

GEORGE TEVDORASHVILI; DAVID TEVDORASHVILI; MARIAM ANDGULADZE; MARIAM TEVDORASHVILI

doi:10.52340/jecm.2023.05.22

EFFECTS OF ORAL DEHYDROEPIANDROSTERONE (DHEA) SUPPLEMENTATION ON HORMONAL PROFILE AND MENOPAUSAL CLINICAL SYMPTOMS IN EARLY POSTMENOPAUSAL SYMPTOMATIC WOMEN

Authors

GEORGE TEVDORASHVILI Tbilisi State Medical University
DAVID TEVDORASHVILI Medical Center „Laser”, Department of Obstetrics and Gynecology; Tbilisi, Georgia
MARIAM ANDGULADZE Medical Center „Laser”, Department of Obstetrics and Gynecology; Tbilisi, Georgia
MARIAM TEVDORASHVILI Medical Center „Laser”, Department of Obstetrics and Gynecology; Tbilisi, Georgia

DOI:

https://doi.org/10.52340/jecm.2023.05.22

Keywords:

Dehydroepiandrosterone, hormonal profile, menopausal clinical symptoms

Abstract

Dehydroepiandrosterone (DHEA) and its sulfate (DHEAs) are steroid hormones secreted by the adrenal glands. The aging process is associated with decreased levels of DHEA and DHEAs, which are the initial causes of many age-related changes. We aimed to evaluate the effects of oral administration of DHEA (50mg/day) on hormonal profile, menopausal clinical symptoms and overall well-being in early postmenopausal symptomatic women. DHEA administration had a significant effect on certain endocrine parameters, was associated with improvements of menopausal physical symptoms, sexual function and psycho-emotional parameters. On this basis we can assume, that DHEA may be considered as a potentially effective medication for MHT. However, conducting further, more specific clinical trials are needed.

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Author Biography

GEORGE TEVDORASHVILI, Tbilisi State Medical University

Department of Obstetrics and Gynecology

References

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