STUDY OF THE SAFETY OF USING MINERAL-RADON WATERS OF TSKALTUBO

STUDY OF THE SAFETY OF USING MINERAL-RADON WATERS OF TSKALTUBO

Authors

  • MIKHEIL GOGEBASHVILI
  • GARY GREBENCHUK
  • EREMIA TULASHVILI
  • NAZI IVANISHVILI
  • SOFIO KALMAKHELIDZE
  • MARIAM SHUBITIDZE

DOI:

https://doi.org/10.52340/jecm.2023.03.04

Keywords:

Radon, gamma-irradiation, hormesis, Tskaltubo

Abstract

Concentration of Radon in Tskaltubo geothermal waters equals to 40-100 Bq/l, and when inhaled, this number does not exceed 37 Bq/m3. Inhaled concentration is characterized by minimal radioactivie parameters and is irrelevant to the characteristic parameters listed in the classification, what indicates that the healing properties of Tskaltubo mineral waters cannot be attributed only to the Radon concentration. During inhalation therapy, radiation exposure is formed by various salt ions and gas of mineral water, in conditions of high humidity and temperature. Furthermore, the activation of physiological-biochemical processes (Hormesis) not only dependents on the dose of radon absorbed by the body, but is the result of different complex factors joint action that require further research.

Downloads

Download data is not yet available.

References

Indrin J., Chetty at all. Technology for Innovation in Radiation Oncology. Int J Radiat Oncol Biol Phys. 2015 Nov 1; 93(3): 485–492.

Claudio Fiorino, Matthias Guckenberger, Marco Schwarz, Uulke A van der Heide, Ben Heijmen. Technology-driven research for radiotherapy innovation. Mol Oncol. 2020 Jul; 14(7): 1500–1513.

Lilla Pawlik-Sobecka, Joanna Górka-Dynysiewicz, Jadwiga Kuciel-Lewandowska. Balneotherapy with the Use of Radon-Sulphide Water: The Mechanisms of Therapeutic Effect. Appl. Sci. 2021, 11, 2849.

Marine Nikolaishvili, Zaqaria Nanobashvili, Nodar Mitagvaria, Gvantsa Chkadua, Tea Museliani, Khatuna Dondoladze, Gogi Jikia. Assessment of integrated antioxidant systems and hormezis effect of radon in experimental studies. Journal of Biosciences and Medicines. 2022, Vol.10, #3, p.212-227.

Elene Sakvarelidze, Marine Nikolaishvili, Mamuka Margvelashvili, Zurab Sakvarelidze, Sesili Beriashvili. Effects of small doses of radon during the use of removable orthopedic structures in dental practice, Experimental and Clinical Medicine, 2023; 1:23-28.

M Nikolaishvili, Z Nanobashvili, N Mitagvaria, Radon hormesis in epileptic pathogenesis and predictors of oxidative stress. Georgian Medical News, 2021, 152-158

K Dolidze, V Margvelashvili, M Nikolaishvili, T Suladze, M Pkhaladze, Study of the hygienic characteristics of the oral cavity under the complex effect of photodynamic therapy and Tskaltubo spring water radon hormesis. Georgian Medical News, 2021, 54-59.

M Nikolaishvili, D Zurabashvili, T Museliani, G Jikia, G Parulava, Complex study of biological effect of Tskhaltubo radon water inhalation. Georgian Medical News, 2019, 113-118

M Nikolaishvili, S Omiadze, T Shishniashvili, D Zurabashvili, G Parulava. Complex study of medicinal properties of radon in mineral water of tskaltubo and oral cavity mineralization recovery in patients with periodontitis. Georgian medical news, 2018, 39-43.

T Mchedluri, D Oniani, T Oniani, T Museliani, G Grebenchuk, Mechanisms of Radon influence during inhalation of Tskaltubo mineral water vapor. Proceedings of the Georgian National Academy of Sciences, 2006, 32 (1): 97-101.

S Omiadze, M Nikolaishvili, T Shishniashvili. Inhalation therapy by radon from Tskhaltubo region in clinical and biochemical studies in patients with periodontitis. Georgian Medical News, 2020, 82-86

Marina Nikolaishvili, Zakaria Nanobashvili, Nodar Mitagvaria, Gvantsa Chkadua, Tea Museliani, Gogi Jikia, Irine Bilanishvili, Khatuna Dondoladze. The Level of Individual Biochemical Constants of the Brain of in the Krushinsky-Molodkina Inbred Rat Strain against the Background of Radon Inhalation During Epilepsy, Open Access Macedonian Journal of Medical Sciences, 2022, 10(B): 2555-65.

N Chkheidze, E Giorgadze, M Nikolaishvili, A Malazonia, The Effect of Low Doses of Radon on Ghrelin and Glucose Levels in Rats with Multiple Low-Dose Streptozotoccin-induced Type 2 Diabetes Mellitus. Open Access Macedonian Journal of Medical Sciences, 2022, 10(B): 1468-1472

M Nikolaishvili, Z Nanobashvili, N Mitagvaria, G Chkadua, T Museliani. Assessment of integrated antioxidant systems and hormezis effect of radon in experimental studies. Journal of Biosciences and Medicines 2022, 10 (3): 212-227.

K Dondoladze, M Nikolaishvili, D Zurabashvili. The effect of balneotherapy on the oxidative system and changes in anxiety behavior, enhanced by low doses of radon. International Journal of Radiation Biology, 2021, 97(10), 1461-1469

M Nikolaishvili, J Adamia, N Mosemgvdlishvili, Oral condition and radon hormesis in patients undergoing orthhodontic treatment. Experimental and Clinical Medicine Georgia, 2021; 1:50-63.

И.Н. Гудков, А.Г. Кудяшева, А.А. Москалёв. Радиобиология с основами радиоэкологии. Издательство СыктГУ, Институт биологии Коми НЦ 2014, 512с.

Гродзинский Д.М. Radiobiologia, Kiyv, Libidz, 2000, 448c.

I.M. Gudkov, M.M. Vinichuk, Radiobiology & Radioecology. Kyiv, 2019, 399p

H. Grebenchuk, M. E. Gogebashvili and N. I. Ivanishvili. The Problem of Lead 210Pb in the Manifestation of the Effects of Radon Exposure on Living Organisms: A Conceptual Analysis, In systemic, cellular and molecular mechanisms of physiological functions and their disorders. Nova Science Publishers, (Medicine & Health), New-York, 2021, p.23-35

მიხეილ გოგებაშვილი; დავით ნადარეიშვილი; ნაზი ივანიშვილი; გარი გრებენჩუკი. რადონის ზეგავლენით ბიოლოგიური ობიექტის მიერ რადიაციის შთანთქმული დოზის განსაზღვრის მეთოდი. პატენტი P 2020 7206 B, რეგისტრაციის თარიღი: 21.12.2020.

Julson B., Mizon K., Smith H. et al. Evidence Central: Skeletal lead release during bore resorption: effect of biphosphate treatment in apilot study // Environ. Health Perspect. 2002; 110:1017-1024.

Popovic M., Mc Neit F.E., Chettle D.R. et al. Impact of occupational exposure on lead levels in women //Environ. Health Perspect. 2003; 113(4):478-484.

Fischbach F.T. Manual of Laboratory and Diagnostic Tests / F.T.Fishbach, M.B.Dunning. - N/Y.: Lippincott Willians Wilkins, 2008. - 1344p.

Измеров Н.Ф. Свинец и здоровье. Гигиенический и медико-биологический мониторинг / Н.Ф. Измеров. – М., 2000. - 256 с.

Корбакова А.И., Соркина Н.С., Молодкина Н.Н. и др. Свинец и его действие на организм (обзор литературы) // Медицина труда и промышленная экология. 2001; 5:29-34.

Downloads

Published

2023-09-18

How to Cite

GOGEBASHVILI, M., GREBENCHUK, G., TULASHVILI, E., IVANISHVILI, N., KALMAKHELIDZE, S., & SHUBITIDZE, M. (2023). STUDY OF THE SAFETY OF USING MINERAL-RADON WATERS OF TSKALTUBO. Experimental and Clinical Medicine Georgia, (3). https://doi.org/10.52340/jecm.2023.03.04

Issue

Section

Articles
Loading...