RATIONAL TREATMENT OF BACTERIAL VAGINOSIS
DOI:
https://doi.org/10.52340/jecm.2023.02.03Keywords:
Bacterial vaginosis (BV), Clindamicin, Fluomyzin, Gynoflor – EAbstract
Comparative analysis of 3 therapeutical schemes was made. 42 patients of the I group used antibiotic and then probiotic; 40 patients of II group received antiseptic and then probiotic. 38 patients of III group were using antiseptic and then estriol containing probiotic. Both combinative schemes, applied in the I and II groups, were characterized by the identical results. Maximal effectiveness of therapy was achieved in the III group.
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Atashili J. et al. Bacterial vaginosis and HIV acquisition: a metanalysis of publ. studies. AIDS.2008;22:1493-1501.
Federal clinical recommendations of the ROAG; „Diagnosis and treatment of diseases accompanied by pathological secretions from the genital tract of women“. 2019.
Larsson P.G., Platz Cristensen J.J. et al. Incidence of pelvic inflammatory disease after first trimester legal abortion in women with lacterial vaginosis after treatment with metronidazole: a double – blind, randomized study. „AM. J. Obstet. Gynecol.“ 1992; 166 (1Pt.1): 100-103.
Macklaim J.M., Clemente J.C., Knight R., et al. Changes in vaginal microbiota following antimicrobial and probiotic therapy. Microb. Ecol. Health Dis. 2015; 26: 277-99.
Mishra R.K. et al. New life for an old antibiotic. ACS Appl. Mater. Interfaces. 2015; 7(13): 7324-33.
Ozkinay E., Terek M.C., et al. The effectiveness of live lactobacilli in combination with low dose estriol (Gynoflor) to restore the vaginal flora after treatment of vaginal infections. BJOG. 2005; 112(2): 234-40. https://dx.doi.org/10.1111/j.1471-0528.2004.00329.x
Santiago G., Grob P., Verstraelen H., et al. Susceptibility testing of Atopobium vaginae for dequalinium chloride BMC Res. Notes. 2012;5:151. https://dx.doi.org/10.1186/1756-0500-5-151.
Sgibnev A.V., Kremleva E.A. Metabolites of the normal vaginal microflora increase the activity of antibiotics. Obstetrics and gynecology. 2017; (3): 108-14.
Sgibnev A. Kremleva E. Influence of hydrogen peroxide, lactic acid and surfactants from vaginal lactobacilli on the antibiotic sensitivity of opportunistic bacteria. Probiotics and antimicrobial proteins. 2017; 9(2): 131-41.
The cervic, vagina, vulva, physiology, pathology, colposcopy, aesthetic correction: a guide for practitioners; Edited by S.I. Rogovskaya, E.V. Lipova. Moscow: publishing house of the journal status Praesens; 2014, 250p.
Van de Wijgert J.H., Morison C.S. et al. Bacterial vaginosis and vaginal yeast, but not vaginal cleansing; increase HIVI acquisition in African women. „J. Acquir. Immune. Defc. Syndr.“ 2008; 48:203-209.
Weisseabacher E.R., Donders G., et al. A comparison of dequalinium chloride vaginal tablets (Fluomizin) and clindamycin vaginal cream in the treatment of bacterial vaginosis: a single-blind, randomized clinical trial of efficacy and safety. Gynecol. Obstet. Invest. 2012; 73(1): 8-15. https://dx.doi.org/10.1159/000332398.
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