Аннотация
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Библиографические ссылки
1. Furman D, Campisi J, Verdin E, et al. Chronic inflammation in the etiology of disease across the life span. Nat Med. 2019;25(12):1822-1832.DOI: 10.1038/s41591-019-0675-0
2. Medzhitov R. The spectrum of inflammatory responses. Science. 2021;374(6571):1070-1075.DOI: 10.1126/science.abi5200
3. Buonacera A, Stancanelli B, Colaci M, Malatino L. Neutrophil to lymphocyte ratio: An emerging marker of the relationships between the immune system and diseases. Int J Mol Sci. 2022;23(7):3636.DOI: 10.3390/ijms23073636
4. Forget P, Khalifa C, Defour JP, et al. What is the normal value of the neutrophil-to-lymphocyte ratio? BMC Res Notes. 2017;10(1):12.DOI: 10.1186/s13104-016-2335-5
5. Afari ME, Bhat T. Neutrophil to lymphocyte ratio (NLR) and cardiovascular diseases: An update. Expert Rev Cardiovasc Ther. 2016;14(5):573-7.DOI: 10.1586/14779072.2016.1154788
6. Lagunas-Rangel FA. Neutrophil-to-lymphocyte ratio and lymphocyte-to-C-reactive protein ratio in patients with COVID-19 (COVID-19): A meta-analysis. J Med Virol. 2020;92(10):1733-1734.DOI: 10.1002/jmv.25819
7. Henry BM, de Oliveira MHS, Benoit S, et al. Hematologic, biochemical and immune biomarker abnormalities associated with severe illness and mortality in coronavirus disease 2019 (COVID-19): a meta-analysis. Clin Chem Lab Med. 2020;58(7):1021-1028.DOI: 10.1515/cclm-2020-0369
8. Meghan A. Cupp, Margarita Cariolou, Ioanna Tzoulaki, et al. Neutrophil to lymphocyte ratio and cancer prognosis: an umbrella review of systematic reviews and meta-analyses of observational studies. BMC Med. 2020;18:360.DOI: 10.1186/s12916-020-01817-1
9. Mantovani A, Cassatella MA, Costantini C, Jaillon S. Neutrophils in the activation and regulation of innate and adaptive immunity. Nat Rev Immunol. 2011; 11(8):519-31.DOI: 10.1038/nri3024
10. Papayannopoulos V. Neutrophil extracellular traps in immunity and disease. Nat Rev Immunol. 2018;18(2):134-147.DOI: 10.1038/nri.2017.105
11. Coffelt SB, Wellenstein MD, de Visser KE. Neutrophils in cancer: Neutral no more. Nat Rev Cancer. 2016;16(7):431-446.DOI: 10.1038/nrc.2016.52
12. Yang Li, Wei Wang, Fan Yang, Yanan Xu, Chang Feng, Yong Zhao. The regulatory roles of neutrophils in adaptive immunity. Cell Commun Signal. 2019;17(1):147. doi: 10.1186/s12964-019-0471-y.
13. Lowsby, R.; Gomes, C.; Jarman, I.; Lisboa, P.; Nee, P.A.; Vardhan, M.; Eckersley, T.; Saleh, R.; Mills, H. Neutrophil to lymphocyte count ratio as an early indicator of blood stream infection in the emergency department. Emerg. Med. J. 2015, 32, 531-534.
14. Zahorec R. Ratio of neutrophil to lymphocyte counts-rapid and simple parameter of systemic inflammation and stress in critically ill. Bratisl Lek Listy. 2001;102(1):5-14.
15. Karakonstantis, S.; Kalemaki, D.; Tzagkarakis, E.; Lydakis, C. Pitfalls in studies of eosinopenia and neutrophil-to-lymphocyte count ratio. Infect. Dis. 2018, 50, 163-174.
16. Agata Buonacera, Benedetta Stancanelli, Michele Colaci, Lorenzo Malatino. Neutrophil to Lymphocyte Ratio: An Emerging Marker of the Relationships between the Immune System and Diseases. Int. J. Mol. Sci. 2022, 23, 3636. https://doi.org/10.3390/ijms23073636
17. Uthamalingam S, Patvardhan EA, Subramanian S, Ahmed W, Martin W, Daley M, Capodilupo R.Utility of the neutrophil to lymphocyte ratio (NLR) in predicting long term mortality in patients with acute decompensated heart failure.Am J Cardiol. 2011;107(4):433-438.DOI: 10.1016/j.amjcard.2010.09.039
18. Adamstein NH, MacFadyen JG, Rose LM, et al. The neutrophil-lymphocyte ratio and incident atherosclerotic events: analyses from five contemporary randomized trials. Eur Heart J. 2021; 42(9):896-903. DOI: 10.1093/eurheartj/ehaa1034
19. Vakhshoori M, Nemati S, Sabouhi S, et al. Neutrophil to lymphocyte ratio (NLR) prognostic effects on heart failure; a systematic review and meta analysis. BMC Cardiovasc Disord. 2023;23:555.DOI: 10.1186/s12872-023-03572-6
20. Libby P. Inflammation in atherosclerosis. Arterioscler Thromb Vasc Biol. 2012;32(9):2045-51. DOI: 10.1161/ATVBAHA.108.179705
21. Shah, N.; Parikh, V.; Patel, N.; Patel, N.; Badheka, A.; Deshmukh, A.; Rathod, A.; Lafferty, J. Neutrophil lymphocyte ratio significantly improves the Framingham risk score in prediction of coronary heart disease mortality: Insights from the National Health and Nutrition Examination Survey-III. Int. J. Cardiol. 2014, 171, 390-397.
22. Núñez, J.; Núñez, E.; Bodí, V.; Sanchis, J.; Miñana, G.; Mainar, L.; Santas, E.; Merlos, P.; Rumiz, E.; Darmofal, H.; et al. Usefulness of the Neutrophil to Lymphocyte Ratio in Predicting Long-Term Mortality in ST Segment Elevation Myocardial Infarction. Am. J. Cardiol. 2008, 101, 747-752.
23. Azab,B.; Zaher, M.; Weiserbs, K.F.; Torbey, E.; Lacossiere, K.; Gaddam, S.; Gobunsuy, R.; Jadonath, S.; Baldari, D.; McCord, D.; et al. Usefulness of Neutrophil to Lymphocyte Ratio in Predicting Short- and Long-Term Mortality After Non-ST-Elevation Myocardial Infarction. Am. J. Cardiol. 2010, 106, 470-476.
24. Cho,K.H.; Jeong, M.H.; Ahmed, K.; Hachinohe, D.; Choi, H.S.; Chang, S.Y.; Kim, M.C.; Hwang, S.H.; Park, K.-H.; Lee, M.G.; et al. Value of Early Risk Stratification Using Hemoglobin Level and Neutrophil-to-Lymphocyte Ratio in Patients With ST-Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention. Am. J. Cardiol. 2011, 107, 849-856.
25. Tamhane, U.U.; Aneja, S.; Montgomery, D.; Rogers, E.-K.; Eagle, K.A.; Gurm, H.S. Association Between Admission Neutrophil to Lymphocyte Ratio and Outcomes in Patients with Acute Coronary Syndrome. Am. J. Cardiol. 2008, 102, 653-657.
26. Papa, A.; Emdin, M.; Passino, C.; Michelassi, C.; Battaglia, D.; Cocci, F. Predictive value of elevated neutrophil-lymphocyte ratio on cardiac mortality in patients with stable coronary artery disease. Clin. Chim. Acta 2008, 395, 27-31.
27. Corriere, T.; Di Marca, S.; Cataudella, E.; Pulvirenti, A.; Alaimo, S.; Stancanelli, B.; Malatino, L. Neutrophil-to-Lymphocyte Ratio is a strong predictor of atherosclerotic carotid plaques in older adults. Nutr. Metab. Cardiovasc. Dis. 2018, 28, 23-27.
28. Mannarino, M.R.; Bianconi, V.; Gigante, B.; Strawbridge, R.J.; Savonen, K.; Kurl, S.; Giral, P.; Smit, A.; Eriksson, P.; Tremoli, E.; et al. Neutrophil to lymphocyte ratio is not related to carotid atherosclerosis progression and cardiovascular events in the primary prevention of cardiovascular disease: Results from the IMPROVE study. BioFactors 2021, 48, 100-110.
29. De Jager, C.P.; Van Wijk, P.T.; Mathoera, R.B.; De Jongh-Leuvenink, J.; Van Der Poll, T.; Wever, P.C. Lymphocytopenia and neutrophil-lymphocyte count ratio predict bacteremia better than conventional infection markers in an emergency care unit. Crit. Care 2010, 14, R192.
30. Huang,Z.; Fu, Z.; Huang, W.; Huang, K. Prognostic value of neutrophil-to-lymphocyte ratio in sepsis: A meta-analysis. Am. J. Emerg. Med. 2020, 38, 641-647.
31. Gurol, G.; Ciftci, I.H.; Terzi, H.A.; Atasoy, A.R.; Ozbek, A.; Koroglu, M. Are There Standardized Cutoff Values for Neutrophil Lymphocyte Ratios in Bacteremia or Sepsis? J. Microbiol. Biotechnol. 2015, 25, 521-525.
32. Liu, S.; Wang, X.; She, F.; Zhang, W.; Liu, H.; Zhao, X. Effects of Neutrophil-to-Lymphocyte Ratio Combined with Interleukin-6 in Predicting 28-Day Mortality in Patients with Sepsis. Front. Immunol. 2021, 12, 639735.
33. Jang, J.Y.; Yoo, G.; Lee, T.; Uh, Y.; Kim, J. Identification of the robust predictor for sepsis based on clustering analysis. Sci. Rep. 2022, 12, 2336.
34. Donath MY, Meier DT, Böni Schnetzler M. Inflammation in the Pathophysiology and Therapy of Cardiometabolic Disease. Endocr Rev. 2019;40(4):1080-1091. DOI: 10.1210/er.2019-00002
35. Lou M, et al. Relationship between neutrophil-lymphocyte ratio and insulin resistance in newly diagnosed type 2 diabetes mellitus patients. BMC Endocr Disord. 2015;15:9.DOI: 10.1186/s12902-015-0002-9
36. Liu CC, et al. Neutrophil to lymphocyte ratio in metabolic syndrome. Medicine (Baltimore). 2019; 98 (43):e17537. DOI: 10.1097/MD.0000000000017537
37. Mayank Mahajan, Manoj Kumar Prasad, Chanchal Ashok, Rishi Tuhin Guria, Sujeet Marandi, Vidyapati, Sudhanshu Subrat, Anindya Chowdhury.The Correlation of the Neutrophil-to-Lymphocyte Ratio With Microvascular Complications in Patients With Diabetes Mellitus. Cureus 2023;15(9): e44601. DOI 10.7759/cureus.44601
38. Templeton AJ, et al. Prognostic role of neutrophil-to-lymphocyte ratio in solid tumors: a systematic review and meta-analysis. J Natl Cancer Inst. 2014;106(6):dju124. DOI: 10.1093/jnci/dju124
39. Rugambwa TK, et al. Neutrophil-lymphocyte ratio and platelet-lymphocyte ratio as potential predictive markers of treatment response in cancer patients treated with immune checkpoint inhibitors: a systematic review and meta-analysis. Front Oncol. 2023;13:1181248. doi: 10.3389/fonc. 2023.1181248
40. Kim CG, et al. Hyperprogressive disease during PD-1/PD-L1 blockade in patients with non-small-cell lung cancer. Ann Oncol. 2019;30(7):1104-1113. DOI: 10.1093/annonc/mdz123
41. Lianos, G.D.; Alexiou, G.A.; Exarchos, C.; Rausei, S.; Mitsis, M.; Voulgaris, S. Prognostic significance of neutrophil-to-lymphocyte ratio in several malignancies: Where do we stand? Biomarkers Med. 2020, 14, 169-172.
42. Banna, G.L.; Di Quattro, R.; Malatino, L.; Fornarini, G.; Addeo, A.; Maruzzo, M.; Urzia, V.; Rundo, F.; Lipari, H.; De Giorgi, U.; et al. Neutrophil-to-lymphocyte ratio and lactate dehydrogenase as biomarkers for urothelial cancer treated with immunotherapy. Clin. Transl. Oncol. 2020, 22, 2130-2135.
43. Arvanitakis, K.; Mitroulis, I.; Germanidis, G. Tumor-Associated Neutrophils in Hepatocellular Carcinoma Pathogenesis, Prognosis, and Therapy. Cancers 2021, 13, 2899.
44. Song, M.; Graubard, B.I.; Rabkin, C.S.; Engels, E.A. Neutrophil-to-lymphocyte ratio and mortality in the United States general population. Sci. Rep. 2021, 11, 464