Study of correlation of polyphenolic content and antioxidant activity of georgian propolis

Abstract

In recent years, were developed very interesting and important scientific direction to evaluate the pharmacological profile of Propolis by their geographic origin and chemical content. The bibliography shows that study results commonly are divers and need more deep investigations. In re- spect of this challenge, was designed our work to investigate the possible correlation of antioxidant activity of Geor- gian Propolis with its polyphenolic content. Based on the abovementioned, the aim of our study was determination the polyphenolic content of Propolis samples from different regions of Georgia, and investigation of their antioxidant activity. As a method of study was spectrophotometry, by determination of samples optical density at 290 nm (content of polyphenols) and 517 nm (antioxidant activity with DPPH). Propolis samples were chosen from different sides of Georgia: Akhaltsikhe, Mestia, Chaqvi, Khulo, Sachkhere, Zestafoni, Signagi.

Based on conducted studies, was determined that all samples have a high content of polyphenolic content and their quantity varies from 43.39-87.5%. Samples have high antioxidant activity as well.

Besides, of evident correlation of polyphenolic content and antioxidant activity, just only in one case the dependence was nonlinear: in samples of Samtskhe-Javakheti (Akhaltshikhe) the concentration of polyphenols was 64.31% and antioxidant activity was - 89.0%. Due to even one case, we believe that the additional studies should be done in this direction, as not only polyphenols may be responsible for antioxidant activity, and other compounds of Propolis or their synergic action also cause the same action.