Hepatitis C association with porphyria cutanea tarda and lichen planus (clinical case review)

Abstract

Hepatitis C is an inflammatory liver disease associated with many extrahepatic manifestations (1, 3). Its role in the development of such skin diseases as lichen ruber planus, porphyria cutanea tarda, cryoglobulinemia, necrotizing acral erythema, nodular prurigo, and psoriasis is actively discussed. We review a sporadic case of an association between porphyria cutanea tarda, lichen planus, and hepatitis C.

A clinical case. Patient I. A. 54 years old. Objectively: on the body - monomorphic, lily-colored, polygonal-shaped elements with an umbilical depression in the center. On the front surface of the tibia - dark purple, large, hypertrophic, and hyperkeratotic papules. On the palms of the hands and feet - yellow, hyperkeratotic plaques and dense erythematous papules. On the flexor surfaces of the distal phalanges - bullae. On the dorsal surface of the palm, along with warty papules, there were blisters, the emergence of which the patient associates with slight pressure and insolation. Urinary examination with Wood's lamp showed a coral pink fluorescence.