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Abstract
Macrolides are one of the most interesting and promising classes of antibiotics. Azithromycin is a third-generation, 15-membered macrolide - azalide. Its pharmacokinetics is characterized by a combination of low serum concentrations, high tissue concentrations and an extended tissue elimination half-life. Azithromycin is particularly noted for high and prolonged concentrations at the site of infection.
Azithromycin 500.0 mg capsules, called “Azimac”, is produced by Georgian pharmaceutical enterprise “GMP”.
Purpose of the investigation was – determination of in vitro outlet of Azithromycin in “Azimac” 500 mg capsules, produced by the Georgian pharmaceutical company “GMP”, using the High-Pressure Liquid Chromatography Method (HPLC)
According to the received results, average percent quantity outlet of Azithromycin is 98,80%, (norm not less 75 %). “Azimac” 500 mg capsules containing Azithromycin, produced by the Georgian pharmaceutical company “GMP” are characterized by good outlet quality.