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Abstract
One of the important challenges of the last years of the 21st century is the reduction of synthetic active substances in food, pharmaceuticals and cosmetics.
Propolis is one of the most interesting biologically active product among natural substances.
Propolis is a natural biologically active product and has a diverse chemical composition, but its main constituents are polyphenolic compounds.
The aim of the research was to develop the composition and technology of Propolis gel using natural ingredients. Chitosan was selected as a natural gel-forming polymer, which additionally has antimicrobial activity.
Based on biopharmaceutical studies, the composition of Propolis gel was determined: alcoholic extract of Propolis (30%) 5g, chitosan 3g, glycerin 7.5g, potassium sorbate 0.1g, 30% acetic acid 2g, distilled water up to 100g.
The following indicators of the quality of the prepared Propolis gel were evaluated: solubility, thermostability, colloidal stability, pH, gel distribution, extrusion, rheological characteristics.
The results obtained as a result of the research are satisfactory and meet the relevant requirements.