VITAMIN D STATUS AMONG TBILISI HEALTHY PEDIATRIC POPULATION
DOI:
https://doi.org/10.52340/jecm.2023.04.18Ключевые слова:
hypovitaminosis D, healthy, children, adolescentsАннотация
Objectives. Vitamin D deficiency has been identified as a common worldwide metabolic/endocrine abnormality. There is no published data about vitamin D plasma level in Georgian population. Present study was conducted to reveal vit D status among healthy children from Tbilisi pediatric population.
Material and Methods. The present study was performed to study vit D plasma level in healthy children at age 1 to 15 years. The 3 groups of children were formed – in the I group were included 63 children at age 1 to 5 years; II group formed 50 children at age 5 years +1month to 10 years and III group formed 17 children at age 10years+1 month to 15 years. One moment blood concentrations of 25(OH)D were determined in every study participant.
Results. Mean serum 25(OH) vitamin D level in the I age group was – 35.54ng/ml ± 8.66. In II age group vit D level was 27.71 ± 18.29 ng/ml. In III age group mean serum 25(OH) D level was – 28.31 ± 12.59ng/ml. Comparison of serum 25(OH) vitamin D levels between the I and III study groups revealed a statistically significant difference (p < 0.05). In 14% of healthy adolescents from group III the vit D plasma level was <20ng/ml (16±11.5ng/ml).
Conclusion. Only children <5 years revealed 25(OH)D sufficient plasma concentration. In elder children (groups II and III), were diagnosed Vit D insufficiency. 14% of adolescents revealed vit D deficiency (<20ng/ml).
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Ahmed S, Goldberg GR, Raqib R, et al. Aetiology of nutritional rickets in rural Bangladeshi children. Bone. 2020; 136:115357.
Akhtar S., Vitamin D Status in South Asian Populations - Risks and Opportunities. Review. Crit Rev Food Sci Nutr. 2016 Aug 17; 56(11):1925-40.
Bouillon R, Antonio L. Nutritional rickets: historic overview and plan for worldwide eradication. J Steroid Biochem Mol Biol. 2019; 198:105563.
Cashman KD, Dowling KG, Škrabáková Z, Gonzalez-Gross M, Valtueña J, De Henauw S, et al. Vitamin D deficiency in Europe: pandemic? Am J Clin Nutr. 2016; 103(4):1033-1044.
Chlebna-Sokół D., Konstantynowicz J., Abramowicz P., et al. Evidence of a significant vitamin D deficiency among 9-13-year-old Polish children: results of a multicentre study. European Journal of Nutrition, 2019; 58:2029-2036.
Giustina A, Bouillon R, Binkley N. et al. Controversies in Vitamin D: A Statement From the Third International Conference. JBMR Plus. 2020 Nov 10; 4(12): e10417. doi: 10.1002/jbm4.10417.
Grossman Z, Hadjipanayis A, Stiris T, Del Torso S, et al. Vitamin D in European children-statement from the European academy of Paediatrics (EAP) Eur J Pediatr. 2017; 176(6):829-831.
Hilger J, Friedel A, Herr R, et al. A systematic review of vitamin D status in populations worldwide. Br J Nutr. 2014; 111(1):23-45.
Holick MF, Binkley NC, Bischoff‐Ferrari HA, et al. Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2011; 96(7):1911–30.
Jachvadze M., Gogberashvili K. Assessment of Knowledge Level Among Georgian Parents About Vitamin D Influence on Child’s Health. Questionnaire Survey. GMN, 2020; 10(307):158-161.
Kondratyeva E.I, Zakharova I.N, Ilenkova N.A, et.all. Vitamin D Status in Russian Children and Adolescents: Contribution of Genetic and Exogenous Factors Front. Pediatr. 19 Nov 2020; 8:583206.
Lips P, Cashman KD, Lamberg-Allardt C, et al. Current vitamin D status in European and Middle East countries and strategies to prevent vitamin D deficiency: a position statement of the European Calcified Tissue Society. Eur J Endocrinol 2019; 180:23-54.
Mogire RM, Mutua A, Kimita W, et al. Prevalence of vitamin D deficiency in Africa: a systematic review and meta‐analysis. Lancet Glob Health. 2020; 8(1): e134-42.
Pettifor JM. Calcium and vitamin D metabolism in children in developing countries. Ann Nutr Metab. 2014; 64(2):15-22. doi: 10.1159/000365124.
Saggese G., F., F, et all. Vitamin D in pediatric age: consensus of the Italian Pediatric Society and the Italian Society of Preventive and Social Pediatrics, jointly with the Italian Federation of Pediatricians. Ital J Pediatr. 2018; 44:51. doi: 10.1186/s13052-018-0488-7.