HYDATIDIFORM MOLE

Abstract

A hydatiform mole (also known as a molar pregnancy) is a gestational trophoblastic disease (GTD), which originates from the placenta and can metastasize. It is unique in that the tumor originates from gestational tissue rather than from maternal tissue. Hydatidiform moles (HM) are usually considered the noninvasive form of gestational trophoblastic disease. While hydatidiform moles are typically deemed benign, they are premalignant and do have the potential to become malignant and invasive. This activity describes the pathophysiology, evaluation and management of hydatidiform moles and highlights the role of the interprofessional team in the management of affected patients. Other forms of gestational trophoblastic disease include gestational choriocarcinoma (which can be extremely malignant and invasive) and placental site trophoblastic tumors.