COMBINED TREATMENT OF PATIENTS WITH INTRAEPITHELIAL CERVICAL NEOPLASIA IN COMBINATION WITH CHRONIC UROGENITAL CANDIDIASIS

COMBINED TREATMENT OF PATIENTS WITH INTRAEPITHELIAL CERVICAL NEOPLASIA IN COMBINATION WITH CHRONIC UROGENITAL CANDIDIASIS

Authors

  • IRADA A. TAGYEVA
  • SEVENGE A. ALIEVA
  • AITEN M. RZAEVA
  • GYULTAKIN R. JAVADOVA
  • VUSALYA Z. TAGYEVA

DOI:

https://doi.org/10.52340/jecm.2023.05.02

Keywords:

cervix, papillomavirus, genital candidiasis, antiviral therapy, immunomodulatory therapy.

Abstract

            This paper proves the effectiveness of the treatment of lesions of the cervix with papillomavirus infection in combination with genital candidiasis using a combination of antiviral, immunomodulatory and antifungal drugs.

         Objective. To study the effectiveness of complex treatment of women with mild to moderate cervical intraepithelial neoplasia (CIN 1, CIN 2) in combination with genital candidiasis.

         Subject and methods. 96 women with cervical pathology aged 20-56 years (29±6.7) were examined. All examined women were divided into 2 groups. Cervical screening was performed, including cytological examination of smears, extended colposcopy, targeted biopsy of the affected areas of the cervix, followed by histological examination. PCR with genotyping and the culture method were also used.        

Results and conclusion. Based on the experience of applying an integrated approach to the treatment of patients with HPV infection of the cervix and combined forms of HPV with genital candidiasis, including combined therapy with the use of destructive treatment of lesions of papillomatous growths and the use of drugs with antiviral and immunomodulatory effects, it can be considered effective and most acceptable at the present time. The use of these drugs reduces the likelihood of HPV persistence and recurrence of the disease.

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References

Прилепская В.Н., Новикова Е.П. Возможности раннего лечения и профилактики папилломавирусной инфекции. Гинекология. 2013, том 15, № 1, с.94-97.

Прилепская В.Н., Довлетханова Э.Р. Особенности диагностики, клинической картины и лечения заболеваний, ассоциированных с папилломавирусной инфекцией. Гинекология. Том 15, №5, с.7-12.

Роговская С.И., Бебнева Т.Н. Цервикальная папилломавирусная инфекция. Возможности комбинированной терапии. Акушерство и гинекология. 2016, №10, с.26-32.

Роговская С.И., Липова Е.В. Шейка матки, влагалище, вульва. Руководство для практикующих врачей. М., 2014, 832 с.

Савичева А.М., Башмакова М.А., Краснопольских Т.В. Лабораторная диагностика бактериального вагиноза: Методические рекомендации. ¬СПб: издательство Н-Л, 2014. 28с.

Сухих Г.Т., Прилепская Т.Н. и др. Руководство для врачей. 2012. 192 с.

Хрянин А.А., Тапильская Н.И., Кнорринг Г.Ю. Современные представления о папилломавирусной инфекции: эпидемиология и тактика ведения пациентов с аногенитальными бородавками. Клиническая дерматология и венерология 2020; том 19, №5

Gillet E., Meys J. F., Verstraelen H., et al. Association between bacterial vaginosis and cervical intraepithelial neoplasia: systematic review and meta-analysis. PLoS One. 2012;7(10) doi: 10.1371/journal.pone.0045201.e45201

Huh W. K., Ault K. A., Chelmow D., et al. Use of primary high-risk human papillomavirus testing for cervical cancer screening: interim clinical guidance. Gynecologic Oncology. 2015;136(2):178-182. doi: 10.1016/j.ygyno.2014.12.022.

Kjaer S. K., Frederiksen K., Munk C., Iftner T. Long-term absolute risk of cervical intraepithelial neoplasia grade 3 or worse following human papillomavirus infection: role of persistence. JNCI Journal of the National Cancer Institute. 2010;102(19):1478-1488. doi: 10.1093/jnci/djq356.

Mitra A., MacIntyre D. A., Marchesi J. R., Lee Y. S., Bennett P. R., Kyrgiou M. The vaginal microbiota, human papillomavirus infection and cervical intraepithelial neoplasia: what do we know and where are we going next? Microbiome. 2016;4(1):58. doi:10.1186/s40168-016-0203-0.

Small W., Jr., Bacon M. A., Bajaj A., et al. Cervical cancer: a global health crisis. Cancer. 2017;123(13):2404-2412. doi: 10.1002/cncr.30667

So K. A., Lee I. H., Kim T. J., Lee K. H. Risk factors of persistent HPV infection after treatment for high-grade squamous intraepithelial lesion. Archives of Gynecology and Obstetrics. 2019;299(1):223–227. doi: 10.1007/s00404-018-4936-9.

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Published

2023-10-12

How to Cite

TAGYEVA, I. A., ALIEVA, S. A., RZAEVA, A. M., JAVADOVA, G. R., & TAGYEVA, V. Z. (2023). COMBINED TREATMENT OF PATIENTS WITH INTRAEPITHELIAL CERVICAL NEOPLASIA IN COMBINATION WITH CHRONIC UROGENITAL CANDIDIASIS . Experimental and Clinical Medicine Georgia, (5), 15–19. https://doi.org/10.52340/jecm.2023.05.02

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