ტრანზიტორული ჰიპერტროფიული კარდიომიოპათია დიაბეტიანი დედის ახალშობილში: კლინიკური შემთხვევა

MIRANDA SHERVASHIDZE; ANANO VERDZADZE; KHATIA DOLIDZE; TAMAR SHERVASHIDZE; TEONA TABATADZE; TAMTA VERDZADZE

doi:10.52340/jecm.2026.03.06

Authors

MIRANDA SHERVASHIDZE Batumi Shota Rustaveli State University
ANANO VERDZADZE Batumi Shota Rustaveli State University
KHATIA DOLIDZE Batumi International University
TAMAR SHERVASHIDZE University of Europe; Georgia
TEONA TABATADZE Batumi Shota Rustaveli State University
TAMTA VERDZADZE Batumi International University

DOI:

https://doi.org/10.52340/jecm.2026.03.06

Keywords:

hypertrophic cardiomyopathy, infant, diabetic mother, echocardiography

Abstract

Introduction: Hypertrophic cardiomyopathy (HCM) is a common inherited cardiomyopathy characterized by left ventricular hypertrophy, with an annual pediatric incidence of 0.3–0.5 per 100,000. A distinct subset is transient HCM in infants of diabetic mothers (IDMs), seen echocardiographically in 13–44% of such infants, symptomatic in up to 12.1%.

Case: A male neonate born at 36 6/7 weeks to a mother with insulin-dependent type 2 diabetes and pre-eclampsia developed respiratory distress at birth. Echocardiography showed biventricular hypertrophy with predominant septal thickening (IVSD 0.92 cm), preserved EF (75%), and no outflow obstruction. He was discharged stable on day 11. At one month, repeat echocardiography showed marked regression (IVSD 0.4 cm, EF 81%) without pharmacologic therapy.

Conclusion: Transient HCM in IDMs is a self-limited, hyperinsulinemia-driven condition. Early echocardiographic screening and serial monitoring are essential to distinguish it from genetic HCM and guide management.

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