WHEN AND FOR WHAT PURPOSES COMBINED ALLERGIC DIAGNOSTIC TESTING SHOULD BE EMPLOYED IN CHILDREN

Abstract

In pediatric practice, the issue of allergic diseases has become particularly prominent in recent years. For the purposes of prevention and treatment of these conditions, the identification of allergens is of significant importance. The aim of our study was to assess the immunological status of children with allergic diseases. Quantitative levels of IgE were measured, and a comprehensive mixed allergen panel was evaluated.

Result: An open observational study was conducted from 2022 to 2025 at the G.Zhvania University Clinic of Pediatrics, the study included 59 children aged 3 to 13 years. The highest IgE were observed in patients with recurrent bronchitis and bronchial asthma, in whom hypersensitivity to respiratory allergens was detected. In cases of allergic urticaria, where IgE levels were moderately elevated, sensitization was observed to plant pollens as well as animal dander. Patients with allergic rhinitis and conjunctivitis exhibited moderately increased IgE levels, with hypersensitivity primarily associated with seasonal allergens. Patients with normal IgE levels predominantly showed hypersensitivity to food allergens.

Conclusion: The implementation of these findings in clinical practice will enable the rational and timely diagnosis of allergic diseases. From a cost-effectiveness perspective, it is preferable to prioritize the diagnostic assessment of allergens.