CONGENITAL PULMONARY ARTERY STENOSIS DIAGNOSED AFTER COVID-19-ASSOCIATED PNEUMONIA IN AN ELDERLY PATIENT WITH MULTIVALVULAR PATHOLOGY AND SUBSEQUENT SUCCESSFUL SURGICAL TREATMENT
DOI:
https://doi.org/10.52340/jecm.2025.06.01Keywords:
Pulmonary stenosis, Covid-associated, combined defect, balloon valvuloplastyAbstract
Congenital pulmonary artery stenosis is predominantly caused by genetic factors and embryonic developmental defects. Due to its association with other congenital heart anomalies, clinical manifestations are often complex and typically present during childhood or adolescence. Diagnosis at an advanced age is extremely rare. Contributing factors such as viral infections can provoke symptom onset.
This paper presents the clinical case of a 69-year-old male patient diagnosed with congenital pulmonary artery stenosis following COVID-19-associated pneumonia. The case was further complicated by comorbidities including combined valvular defect, ischemic cardiomyopathy, essential hypertension, atherosclerotic heart disease, secondary pulmonary hypertension, stage III chronic kidney disease, obesity caused by excessive caloric intake, and type 2 diabetes mellitus. The patient underwent surgical treatment including bioprosthetic replacement of the aortic and pulmonary valves, transannular patch enlargement of the right ventricular outflow tract, and mitral valve annuloplasty. Despite the initially unfavorable prognosis, symptom severity decreased and the patient's condition improved significantly during follow-up.
Downloads
References
Joseph Heaton; Maria S. Horenstein; Chris Kyriakopoulos. „Pulmonary Stenosis„ October 6, 2024. https://www.ncbi.nlm.nih.gov/books/NBK560750/
Federico Marchini, Sofia Meossi, Giulia Passarini, Gianluca Campo, Rita Pavasini.“Pulmonary Valve Stenosis: From Diagnosis to Current Management Techniques and Future .Prospects” 30 June 2023. https://pmc.ncbi.nlm.nih.gov/articles/PMC10320808/pdf/vhrm-19-379.pdf
Percutaneous Balloon Dilation of the Pulmonary Valve in a 79-Year-Old With Congenital Pulmonary Valve Stenosis - CASE Matthew C. Schwartz et al. North Carolina „Percutaneous Balloon Dilation of the Pulmonary Valve in a 79-Year-Old With Congenital Pulmonary Valve Stenosis“ 08.11.2023
Lesieur E, Zaffran S, et al. Prenatal screening and diagnosis ofpulmonary artery anomalies”,2023; https://obgyn.onlinelibrary.wiley.com/doi/epdf/10.1002/uog.26078
Aline Wolter, Natalia Markert et al. Natural history of pulmonary atresia with intact ventricular septum (PAIVS) and critical pulmonary stenosis (CPS) and prediction of outcome“, 2021; https://pmc.ncbi.nlm.nih.gov/articles/PMC8164597/pdf/404_2020_Article_5929.pdf
https://pmc.ncbi.nlm.nih.gov/articles/PMC8923057/pdf/nihms-1781265.pdf. Transcription Factor Protein Interactomes Reveal Genetic Determinants in Heart Disease.2023 March 03
https://pmc.ncbi.nlm.nih.gov/articles/PMC9388589/pdf/nihms-1811057.pdf „Prevalence of Genetic Diagnoses in a Cohort with Valvar Pulmonary Stenosis“ K. Nicole Weaver et al. on behalf of the Pediatric Cardiac Genomics.Consortium Investigators. 2022 August 15
https://pmc.ncbi.nlm.nih.gov/articles/PMC7477980/pdf/bcr-2020-235190.pdf „Case of calcific tricuspid and pulmonary valve stenosis“ -Yash Paul Sharma, Prashant Kumar Panda, Lipi Uppal, Uma Debi, 20 August 2020
The impact of COVID-19 vaccination on patients with congenital heart disease in England: a case-control study. Catriona Harrison et al. On behalf of the CVD-COVID-UK/ COVID-IMPACT consortium 5 September 2024
https://pmc.ncbi.nlm.nih.gov/articles/PMC9619476/pdf/ldac022.pdf „COVID-19 and the heart“ Cardiovascular Department, King’s College Hospital NHS Foundation Trust, London SE5 9RS, UK , 2East.Sussex Healthcare NHS Trust, Hastings TN37 7PT, UK, and 3British Heart Foundation Centre of ResearchExcellence, School of Cardiovascular and Metabolic Medicine & Sciences, Faculty of Life Sciences &Medicine, King’s College London, London SE5 9NU, UK . 2 September 2022
https://pmc.ncbi.nlm.nih.gov/articles/PMC7299644/pdf/heartjnl-2020-317258.pdf Robert M Radke et al.“Adult congenital heart disease and the COVID-19 pandemic” 10 June 2020
https://pmc.ncbi.nlm.nih.gov/articles/PMC8006800/pdf/main.pdf COVID-19 in Adults With Congenital Heart Disease. Craig S. Broberg, Adrienne H. Kovacs, Soraya Sadeghi, 13, 2021
https://pmc.ncbi.nlm.nih.gov/articles/PMC8072585/pdf/viruses-13-00700.pdf. „Long-COVID and Post-COVID Health Complications: An Up-to-Date Review on Clinical Conditions and. Their Possible Molecular Mechanisms“Bruno Silva Andrade et al.: 18 April 2021
https://pmc.ncbi.nlm.nih.gov/articles/PMC10320808/pdf/vhrm-19-379.pdf Pulmonary Valve Stenosis: From Diagnosis to Current Management Techniques and Future Prospects Federico Marchini, Sofia Meossi, Giulia Passarini, Gianluca Campo, Rita Pavasini; 30 June 2023
https://pubmed.ncbi.nlm.nih.gov/38970588/ Considerations in the Diagnosis and Management of Pulmonary Hypertension Associated With Left Heart Disease, Onyedika J Ilonze et al. 2024 Jul 3
https://jamc.ayubmed.edu.pk/index.php/jamc/article/view/9815/3165 “OUTCOME OF BALLOON VALVULOPLASTY IN CHILDREN WITH PULMONARY STENOSIS – SINGLE CENTER EXPERIENCE “Tausif Ahmed et al. 2021
https://www.ncbi.nlm.nih.gov/books/NBK519532/ Balloon Valvuloplasty -Adam Bykowski; Oscar A. Perez; Arun Kanmanthareddy September 12, 2022.
https://pmc.ncbi.nlm.nih.gov/articles/PMC10733597/pdf/ERJ-00763-2023.pdf Adult-onset idiopathic peripheral pulmonary artery stenosis Yudai Tamura, Yuichi Tamura, Ayako Shigeta, Kazuya HosokawaJ 2023
https://pubmed.ncbi.nlm.nih.gov/36647988/ Review of Renal Artery Stenosis and Hypertension: Diagnosis, Management, and Recent Randomized Control Trials. Sadiq F Arab et al. 2022 Jan-Feb
Downloads
Published
How to Cite
Issue
Section
