THE SOURCES AND RISK FACTORS OF LEAD EXPOZURE IN CHILDREN OF ADJARA REGION OF GEORGIA

THE SOURCES AND RISK FACTORS OF LEAD EXPOZURE IN CHILDREN OF ADJARA REGION OF GEORGIA

Authors

  • TAMAR ARAKHAMIA M. Iashvili Children's Central Hospital
  • MAIA KHERKHEULIDZE Tbilisi State Medical University image/svg+xml
  • LIANA ZHORZHOLIANI Tbilisi State University image/svg+xml
  • IVANE CHKHAIDZE M. Iashvili Children's Central Hospital
  • NANI KAVLASHVILI Tbilisi State Medical University image/svg+xml
  • EKA KANDELAKI Tbilisi State Medical University image/svg+xml

DOI:

https://doi.org/10.52340/jecm.2024.02.17

Keywords:

risk factors, lead exposure, children, Adjara Region, Georgia

Abstract

The purpose of our study was to evaluate blood lead level, to determine the main sources of lead exposure in children living in the Adjara region and to identify priority risk factors of high blood lead level. 90 children aged 3-14 years participated in the one-time, cross-sectional study. 61% of studied children had an increase lead concentration in venous blood. The mean lead concentration was 17,25±7,73 μg/dL (median 16.82 μg/dL). The comparative analysis revealed that the probable risk factors of lead exposure in the Adjara region can be attributed to the old house (OR-7,556, CI-2,52-22,60, P-0.000), old renovation (OR-7,884, CI-2, 06-30,08, P-0.001), putting things into mouth and pica (OR–2,791, CI–1,06-7,28, P–0.034). In terms of food high lead levels in blood is associated with frequent consumption of spices (OR-7,556, CI-2,52-22,60, P-0,000), potatoes (OR-9,750, CI-1,13-83,76, P-0,014) and imported confectionery food (OR–3,054, CI–1,11-8.33, P–0,027). So, it is very important to follow the recommendations of CDC for conducting regular screenings of lead level in children for timely identification of lead exposure, for implementation of prevention strategy and adequate management to minimize problems associated with lead exposure.

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References

ბავშვების სისხლში ტყვიის შემცველობა საქართველოში - ეროვნული კვლევის შედეგები. 2019. https://www.unicef.org/georgia/ka/

სურსათში ტყვიასთან ასოცირებული რისკის შეფასების ანგარიში. სოფლის მეურნეობის სამეცნიერო კვლევითი ცენტრი 13.07.2018

Ahmad I, Khan B, Khan S, Khan MT, Schwab AP. Assessment of lead exposure among automobile technicians in Khyber Pakhtunkhwa, Pakistan. Sci Total Environ. 2018 Aug 15;633:293-299. doi: 10.1016/j.scitotenv.2018.03.160. Epub 2018 Mar 22. PMID: 29574373.

Axelrad DA, Coffman E, Kirrane EF, Klemick H. The relationship between childhood blood lead levels below 5µg/dL and childhood intelligence quotient (IQ): Protocol for a systematic review and meta-analysis. Environ Int. 2022 Nov;169:107475. doi: 10.1016/j.envint.2022.107475. Epub 2022 Aug 30. PMID: 36162279; PMCID: PMC9896788.

Baek M, Outrich MB, Barnett KS, Reece J. Neighborhood-Level Lead Paint Hazard for Children under 6: A Tool for Proactive and Equitable Intervention. Int J Environ Res Public Health. 2021 Mar 3;18(5):2471. doi: 10.3390/ijerph18052471. PMID: 33802321; PMCID: PMC7967606.

Bellinger DC. Very low lead exposures and children's neurodevelopment. Curr Opin Pediatr. 2008 Apr;20(2):172-7. doi: 10.1097/MOP.0b013e3282f4f97b. PMID: 18332714.

Boskabady M, Marefati N, Farkhondeh T, Shakeri F, Farshbaf A, Boskabady MH. The effect of environmental lead exposure on human health and the contribution of inflammatory mechanisms, a review. Environ Int. 2018 Nov;120:404-420. doi: 10.1016/j.envint.2018.08.013. Epub 2018 Aug 18. PMID: 30125858.

Dascanio, D., Olaz F.O., Fontaine, A.M.G., et al. The intellectual and academic performance of adolescents contaminated by lead: relation with social skills. Temas em Psicologia, 2012; 20(1):45-59.

Gao, Z., Cao, J., Yan, J., Wang, J., Cai, S., & Yan, C. Blood Lead Levels and Risk Factors among Preschool Children in a Lead Polluted Area in Taizhou, China. BioMed Research International, 2017. https://doi.org/10.1155/2017/4934198

Gordon JN, Taylor A, Bennett PN. Lead poisoning: case studies. Br J Clin Pharmacol. 2002 May;53(5):451-8. doi: 10.1046/j.1365-2125.2002.01580.x. PMID: 11994050; PMCID: PMC1874356.

Grabbe H, Verlander NQ, Iqbal N, Close R, White G, Leonardi GS, Busby A. 'As safe as houses; the risk of childhood lead exposure from housing in England and implications for public health'. BMC Public Health. 2022 Nov 9;22(1):2052. doi: 10.1186/s12889-022-14350-y. PMID: 36352379; PMCID: PMC9644560.

Hauptman M, Bruccoleri R, Woolf AD. An Update on Childhood Lead Poisoning. Clin Pediatr Emerg Med. 2017 Sep;18(3):181-192. doi: 10.1016/j.cpem.2017.07.010. PMID: 29056870; PMCID: PMC5645046.

Hsueh YM, Lee CY, Chien SN, Chen WJ, Shiue HS, Huang SR, Lin MI, Mu SC, Hsieh RL. Association of blood heavy metals with developmental delays and health status in children. Sci Rep. 2017 Mar 2;7:43608. doi: 10.1038/srep43608. PMID: 28252669; PMCID: PMC5333623.

Khan DA, Qayyum S, Saleem S, Ansari WM, Khan FA. Lead exposure and its adverse health effects among occupational worker's children. Toxicol Ind Health. 2010 Sep;26(8):497-504. doi: 10.1177/0748233710373085. Epub 2010 Jun 10. PMID: 20538706.

Kumar, S.; Islam, R.; Akash, P.B.; Khan, H.R.; Proshad, R.; Karmoker, J.; MacFarlan, G.R. Lead (Pb) Contamination in Agricultural Products and Human Health Risk Assessment in Bangladesh. Water Air Soil Pollut. 2022, 233, 257.

Mayans L. Lead Poisoning in Children. Am Fam Physician. 2019 Jul 1;100(1):24-30. PMID: 31259498.

Mandić-Rajčević S, Bulat Z, Matović V, Popević M, Lepić M, Mandić B, Jovanović M, Haufroid V, Žarković M, Bulat P. Environmental and take-home lead exposure in children living in the vicinity of a lead battery smelter in Serbia. Environ Res. 2018 Nov;167:725-734. doi: 10.1016/j.envres.2018.08.031. Epub 2018 Aug 31. PMID: 30236521.

Olufemi AC, Mji A, Mukhola MS. Potential Health Risks of Lead Exposure from Early Life through Later Life: Implications for Public Health Education. Int J Environ Res Public Health. 2022 Nov 30;19(23):16006. doi: 10.3390/ijerph192316006. PMID: 36498077; PMCID: PMC9741093.

UK Government. The Water Supply (Water Quality) Regulations 2016 (as amended) for England. UK Statutory Instruments, No 614, 2016. London: The Stationery Office; 2016. Accessed 11/01/2022 Available from: URL https://www.legislation.gov.uk/uksi/2016/614/contents/made. Last accessed 18 May 2022.

World Health Organization 2019 Lead Poisoning and Health (available at: www.who.int/news-room/fact- sheets/detail/lead-poisoning-and-health Accessed 19 February 2020)

Yabe J, Nakayama SMM, Ikenaka Y, Yohannes YB, Bortey-Sam N, Kabalo AN, Ntapisha J, Mizukawa H, Umemura T, Ishizuka M. Lead and cadmium excretion in feces and urine of children from polluted townships near a lead-zinc mine in Kabwe, Zambia. Chemosphere. 2018 Jul;202:48-55. doi: 10.1016/j.chemosphere.2018.03.079. Epub 2018 Mar 12. PMID: 29554507.

Zeng Z, Huo X, Zhang Y, Xiao Z, Zhang Y, Xu X. Lead exposure is associated with risk of impaired coagulation in preschool children from an e-waste recycling area. Environ Sci Pollut Res Int. 2018 Jul;25(21):20670-20679. doi: 10.1007/s11356-018-2206-9. Epub 2018 May 12. PMID: 29752673.

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Published

2024-06-04

How to Cite

ARAKHAMIA, T., KHERKHEULIDZE, M., ZHORZHOLIANI, L., CHKHAIDZE, I., KAVLASHVILI, N., & KANDELAKI, E. (2024). THE SOURCES AND RISK FACTORS OF LEAD EXPOZURE IN CHILDREN OF ADJARA REGION OF GEORGIA. Experimental and Clinical Medicine Georgia, (2), 82–88. https://doi.org/10.52340/jecm.2024.02.17

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